BDBM34148 CHEMBL371292::piperidinylindole, 7

SMILES O=S(=O)(c1ccccc1)n1cc(C2CCCNC2)c2ccccc12

InChI Key InChIKey=QUUSSZWUXRDTJG-UHFFFAOYSA-N

Data  4 KI  4 EC50

  Tab Delimited (TSV)   2D SDfile   Computed 3D by Vconf -m prep SDfile
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Activity Spreadsheet -- Enzyme Inhibition Constant Data from BindingDB

Found 7 hits for monomerid = 34148   

Target5-hydroxytryptamine receptor 6(Homo sapiens (Human))
Wyeth Research

Curated by ChEMBL
LigandPNGBDBM34148(CHEMBL371292 | piperidinylindole, 7)
Affinity DataKi:  1nMAssay Description:Displacement of [3H]-LSD from cloned human 5-hydroxytryptamine 6 receptor expressed in HeLa cellsMore data for this Ligand-Target Pair
In DepthDetails ArticlePubMed
Target5-hydroxytryptamine receptor 6(Homo sapiens (Human))
Wyeth Research

Curated by ChEMBL
LigandPNGBDBM34148(CHEMBL371292 | piperidinylindole, 7)
Affinity DataKi:  2nM ΔG°:  -12.3kcal/mole EC50:  24nMpH: 7.4 T: 2°CAssay Description:Radioligand binding assays were performed using membranes from HEK-293 transfected with human 5-HT6 receptor. In these membranes the receptor concent...More data for this Ligand-Target Pair
In DepthDetails ArticlePubMed
Target5-hydroxytryptamine receptor 6(Homo sapiens (Human))
Wyeth Research

Curated by ChEMBL
LigandPNGBDBM34148(CHEMBL371292 | piperidinylindole, 7)
Affinity DataKi:  2nMAssay Description:Displacement of [3H]-LSD from cloned human 5-hydroxytryptamine 6 receptor expressed in HeLa cellsMore data for this Ligand-Target Pair
In DepthDetails ArticlePubMed
Target5-hydroxytryptamine receptor 6(Homo sapiens (Human))
Wyeth Research

Curated by ChEMBL
LigandPNGBDBM34148(CHEMBL371292 | piperidinylindole, 7)
Affinity DataKi:  3nMAssay Description:Displacement of [3H]-LSD from cloned human 5-hydroxytryptamine 6 receptor expressed in HeLa cellsMore data for this Ligand-Target Pair
In DepthDetails ArticlePubMed
Target5-hydroxytryptamine receptor 6(Homo sapiens (Human))
Wyeth Research

Curated by ChEMBL
LigandPNGBDBM34148(CHEMBL371292 | piperidinylindole, 7)
Affinity DataEC50:  36nMAssay Description:Effective concentration for cAMP production in HeLa cells expressing human 5-HT6 receptorsMore data for this Ligand-Target Pair
In DepthDetails ArticlePubMed
Target5-hydroxytryptamine receptor 6(Homo sapiens (Human))
Wyeth Research

Curated by ChEMBL
LigandPNGBDBM34148(CHEMBL371292 | piperidinylindole, 7)
Affinity DataEC50:  36nMAssay Description:Effective concentration for cAMP production in HeLa cells expressing human 5-HT6 receptorsMore data for this Ligand-Target Pair
In DepthDetails ArticlePubMed
Target5-hydroxytryptamine receptor 6(Homo sapiens (Human))
Wyeth Research

Curated by ChEMBL
LigandPNGBDBM34148(CHEMBL371292 | piperidinylindole, 7)
Affinity DataEC50:  36nMAssay Description:Effective concentration for cAMP production in HeLa cells expressing human 5-HT6 receptorsMore data for this Ligand-Target Pair
In DepthDetails ArticlePubMed