BDBM343003 1-(4-(2-fluoro-6-methoxy-3-pyridinyl)-2-methoxyphenyl)-N-1,3,4-thiadiazol-2-yl-6-isoquinolinesulfonamide::US9776995, Example 196

SMILES COc1ccc(c(F)n1)-c1ccc(c(OC)c1)-c1nccc2cc(ccc12)S(=O)(=O)Nc1nncs1

InChI Key InChIKey=VGEHAKYGIJOZPB-UHFFFAOYSA-N

Data  1 IC50

  Tab Delimited (TSV)   2D SDfile   Computed 3D by Vconf -m prep SDfile
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Activity Spreadsheet -- Enzyme Inhibition Constant Data from BindingDB

Found 1 hit for monomerid = 343003   

TargetSodium channel protein type 9 subunit alpha(Homo sapiens (Human))
Amgen

US Patent
LigandPNGBDBM343003(1-(4-(2-fluoro-6-methoxy-3-pyridinyl)-2-methoxyphe...)
Affinity DataIC50:  1.05E+3nMAssay Description:HEK 293 cells stably transfected with human Nav1.7 were recorded in whole cell voltage clamp mode with the PatchXpress automated electrophysiology sy...More data for this Ligand-Target Pair
Ligand InfoPC cidPC sid
In DepthDetails US Patent