BDBM343181 4-(2'-fluoro-5,5'-dimethoxy-2-methyl-4-biphenylyl)-N-3-isoxazolyl-7-quinazolinesulfonamide::US9776995, Example 561

SMILES COc1ccc(F)c(c1)-c1cc(OC)c(cc1C)-c1ncnc2cc(ccc12)S(=O)(=O)Nc1ccon1

InChI Key InChIKey=JTIIXSDZUUAEQS-UHFFFAOYSA-N

Data  1 IC50

  Tab Delimited (TSV)   2D SDfile   Computed 3D by Vconf -m prep SDfile
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Similarity at least:  must be >=0.5
Exact match

Activity Spreadsheet -- Enzyme Inhibition Constant Data from BindingDB

Found 1 hit for monomerid = 343181   

TargetSodium channel protein type 9 subunit alpha(Homo sapiens (Human))
Amgen

US Patent
LigandPNGBDBM343181(4-(2'-fluoro-5,5'-dimethoxy-2-methyl-4-biphenylyl)...)
Affinity DataIC50:  89nMAssay Description:HEK 293 cells stably transfected with human Nav1.7 were recorded in whole cell voltage clamp mode with the PatchXpress automated electrophysiology sy...More data for this Ligand-Target Pair
Ligand InfoPC cidPC sid
In DepthDetails US Patent