BDBM343183 4-(2',4'-difluoro-5-methoxy-2-methyl-4-biphenylyl)-N-3-isoxazolyl-7-quinazolinesulfonamide::US9776995, Example 563

SMILES COc1cc(c(C)cc1-c1ncnc2cc(ccc12)S(=O)(=O)Nc1ccon1)-c1ccc(F)cc1F

InChI Key InChIKey=MOJGJPZLIMWJCJ-UHFFFAOYSA-N

Data  1 IC50

  Tab Delimited (TSV)   2D SDfile   Computed 3D by Vconf -m prep SDfile
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Activity Spreadsheet -- Enzyme Inhibition Constant Data from BindingDB

Found 1 hit for monomerid = 343183   

TargetSodium channel protein type 9 subunit alpha(Homo sapiens (Human))
Amgen

US Patent
LigandPNGBDBM343183(4-(2',4'-difluoro-5-methoxy-2-methyl-4-biphenylyl)...)
Affinity DataIC50:  105nMAssay Description:HEK 293 cells stably transfected with human Nav1.7 were recorded in whole cell voltage clamp mode with the PatchXpress automated electrophysiology sy...More data for this Ligand-Target Pair
Ligand InfoPC cidPC sid
In DepthDetails US Patent