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BDBM344197 N-[6-(4-acetylpiperazin-1-yl)-2-ethoxypyridin-3-yl]-5-[2-(2-hydroxyethoxyl)ethyl]-4-oxo-4,5,6,7-tetrahydrofuro[3,2-c]pyridine-3-carboxamide::US9777020, Example 91

SMILES: CCOc1nc(ccc1NC(=O)c1coc2CCN(CCOCCO)C(=O)c12)N1CCN(CC1)C(C)=O

InChI Key: InChIKey=VVADLKUCNLCCHH-UHFFFAOYSA-N

Data: 1 IC50

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Activity Spreadsheet -- Enzyme Inhibition Constant Data from BindingDB

Found 1 hit for monomerid = 344197   
Target/Host
(Institution)
LigandTarget/Host
Links
Ligand
Links
Trg + Lig
Links
Ki
nM
ΔG°
kcal/mole
IC50
nM
Kd
nM
EC50/IC50
nM
koff
s-1
kon
M-1s-1
pHTemp
°C
High affinity nerve growth factor receptor


(Homo sapiens (Human))
BDBM344197
PNG
(N-[6-(4-acetylpiperazin-1-yl)-2-ethoxypyridin-3-yl...)
Show SMILES CCOc1nc(ccc1NC(=O)c1coc2CCN(CCOCCO)C(=O)c12)N1CCN(CC1)C(C)=O
Show InChI InChI=1S/C25H33N5O7/c1-3-36-24-19(4-5-21(27-24)29-10-8-28(9-11-29)17(2)32)26-23(33)18-16-37-20-6-7-30(25(34)22(18)20)12-14-35-15-13-31/h4-5,16,31H,3,6-15H2,1-2H3,(H,26,33)
PDB
MMDB

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US Patent
n/an/a 7n/an/an/an/an/an/a



AbbVie Inc

US Patent




US Patent US9777020 (2017)


BindingDB Entry DOI: 10.7270/Q2T155R7
More data for this
Ligand-Target Pair