BDBM348888 NSC70551::US11041859, Code SPI-06::US9791447, Compound SPI-06

SMILES Cc1ccccc1\N=N\c1cc(c2ccccc2c1N)S([O-])(=O)=O

InChI Key InChIKey=PIWJSAOBFMHEAW-FMQUCBEESA-M

Data  10 IC50

  Tab Delimited (TSV)   2D SDfile   Computed 3D by Vconf -m prep SDfile
Find this compound or compounds like it in BindingDB:
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Similarity at least:  must be >=0.5
Exact match

Activity Spreadsheet -- Enzyme Inhibition Constant Data from BindingDB

Found 10 hits for monomerid = 348888   

TargetSentrin-specific protease 1(Homo sapiens (Human))
City Of Hope

US Patent
LigandPNGBDBM348888(NSC70551 | US11041859, Code SPI-06 | US9791447, Co...)
Affinity DataIC50:  3.90E+3nMAssay Description:The binding of SPI-01 to the enzyme-substrate complex was investigated. CSP analysis was carried out on the 40 kDa complex of 15N-labeled full length...More data for this Ligand-Target Pair
Ligand InfoPC cidPC sid
In DepthDetails US Patent
TargetSentrin-specific protease 2(Homo sapiens (Human))
City Of Hope

US Patent
LigandPNGBDBM348888(NSC70551 | US11041859, Code SPI-06 | US9791447, Co...)
Affinity DataIC50:  3.70E+3nMAssay Description:The binding of SPI-01 to the enzyme-substrate complex was investigated. CSP analysis was carried out on the 40 kDa complex of 15N-labeled full length...More data for this Ligand-Target Pair
Ligand InfoPC cidPC sid
In DepthDetails US Patent
TargetSentrin-specific protease 7(Homo sapiens (Human))
City Of Hope

US Patent
LigandPNGBDBM348888(NSC70551 | US11041859, Code SPI-06 | US9791447, Co...)
Affinity DataIC50:  4.70E+3nMAssay Description:The binding of SPI-01 to the enzyme-substrate complex was investigated. CSP analysis was carried out on the 40 kDa complex of 15N-labeled full length...More data for this Ligand-Target Pair
Ligand InfoPC cidPC sid
In DepthDetails US Patent
TargetSentrin-specific protease/Small ubiquitin-related modifier 1(Homo sapiens (Human))
City Of Hope

US Patent
LigandPNGBDBM348888(NSC70551 | US11041859, Code SPI-06 | US9791447, Co...)
Affinity DataIC50: >6.00E+4nMAssay Description:The inhibitors confer the non-competitive inhibitory mechanism, as shown by nuclear magnetic resonance (NMR) and quantitative enzyme kinetic analysis...More data for this Ligand-Target Pair
Ligand InfoPC cidPC sid
In DepthDetails US Patent
TargetSentrin-specific protease 7(Homo sapiens (Human))
City Of Hope

US Patent
LigandPNGBDBM348888(NSC70551 | US11041859, Code SPI-06 | US9791447, Co...)
Affinity DataIC50:  4.70E+3nMAssay Description:The inhibitors confer the non-competitive inhibitory mechanism, as shown by nuclear magnetic resonance (NMR) and quantitative enzyme kinetic analysis...More data for this Ligand-Target Pair
Ligand InfoPC cidPC sid
In DepthDetails US Patent
TargetSmall ubiquitin-related modifier 1/2(Homo sapiens (Human))
City Of Hope

US Patent
LigandPNGBDBM348888(NSC70551 | US11041859, Code SPI-06 | US9791447, Co...)
Affinity DataIC50:  4.32E+3nMAssay Description:The inhibitors confer the non-competitive inhibitory mechanism, as shown by nuclear magnetic resonance (NMR) and quantitative enzyme kinetic analysis...More data for this Ligand-Target Pair
Ligand InfoPC cidPC sid
In DepthDetails US Patent
TargetSentrin-specific protease/Small ubiquitin-related modifier 2(Homo sapiens (Human))
City Of Hope

US Patent
LigandPNGBDBM348888(NSC70551 | US11041859, Code SPI-06 | US9791447, Co...)
Affinity DataIC50:  1.07E+4nMAssay Description:The inhibitors confer the non-competitive inhibitory mechanism, as shown by nuclear magnetic resonance (NMR) and quantitative enzyme kinetic analysis...More data for this Ligand-Target Pair
Ligand InfoPC cidPC sid
In DepthDetails US Patent
TargetSentrin-specific protease 1(Homo sapiens (Human))
City Of Hope

US Patent
LigandPNGBDBM348888(NSC70551 | US11041859, Code SPI-06 | US9791447, Co...)
Affinity DataIC50:  3.90E+3nMAssay Description:The inhibitors confer the non-competitive inhibitory mechanism, as shown by nuclear magnetic resonance (NMR) and quantitative enzyme kinetic analysis...More data for this Ligand-Target Pair
Ligand InfoPC cidPC sid
In DepthDetails US Patent
TargetSentrin-specific protease 2(Homo sapiens (Human))
City Of Hope

US Patent
LigandPNGBDBM348888(NSC70551 | US11041859, Code SPI-06 | US9791447, Co...)
Affinity DataIC50:  3.70E+3nMAssay Description:The inhibitors confer the non-competitive inhibitory mechanism, as shown by nuclear magnetic resonance (NMR) and quantitative enzyme kinetic analysis...More data for this Ligand-Target Pair
Ligand InfoPC cidPC sid
In DepthDetails US Patent
TargetSentrin-specific protease 2/Small ubiquitin-related modifier 1(Homo sapiens (Human))
City Of Hope

US Patent
LigandPNGBDBM348888(NSC70551 | US11041859, Code SPI-06 | US9791447, Co...)
Affinity DataIC50:  3.62E+3nMAssay Description:The inhibitors confer the non-competitive inhibitory mechanism, as shown by nuclear magnetic resonance (NMR) and quantitative enzyme kinetic analysis...More data for this Ligand-Target Pair
Ligand InfoPC cidPC sid
In DepthDetails US Patent