BDBM349483 (difluoromethyl)-6-(1-::US10206931, Example 291

SMILES CN\C=C(/C=N)c1cc2CCCN(c2cc1C(F)F)c1cccc2NC(=O)C[C@@H](C)Nc12

InChI Key InChIKey=QFKDBDOQGRIRHI-ZNKNOZMVSA-N

Data  2 IC50

  Tab Delimited (TSV)   2D SDfile   Computed 3D by Vconf -m prep SDfile
Find this compound or compounds like it in BindingDB:
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Similarity at least:  must be >=0.5
Exact match

Activity Spreadsheet -- Enzyme Inhibition Constant Data from BindingDB

Found 2 hits for monomerid = 349483   

TargetBromodomain-containing protein 4 [42-168](Homo sapiens (Human))
Genentech

US Patent
LigandPNGBDBM349483((difluoromethyl)-6-(1- | US10206931, Example 291)
Affinity DataIC50:  5.71E+3nMAssay Description:His/Flag epitope tagged BRD4 BD142-168 was cloned, expressed, and purified to. BRD4 binding and inhibition was assessed by monitoring the engagement ...More data for this Ligand-Target Pair
Ligand InfoPC cidPC sid
In DepthDetails US Patent
TargetCREB-binding protein(Homo sapiens (Human))
Genentech

US Patent
LigandPNGBDBM349483((difluoromethyl)-6-(1- | US10206931, Example 291)
Affinity DataIC50:  3nMAssay Description:His/Flag epitope tagged CBP was cloned, expressed, and purified to homogeneity. CBP binding and inhibition was assessed by monitoring the engagement ...More data for this Ligand-Target Pair
Ligand InfoPC cidPC sid
In DepthDetails US Patent