BDBM35013 benzothienopyrimidinone deriv., 13a

SMILES CN(C)Cc1nc2c3cc(ccc3sc2c(=O)[nH]1)C#C

InChI Key InChIKey=VJZFGXCKDFGGEU-UHFFFAOYSA-N

Data  2 KI

  Tab Delimited (TSV)   2D SDfile   Computed 3D by Vconf -m prep SDfile
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Activity Spreadsheet -- Enzyme Inhibition Constant Data from BindingDB

Found 2 hits for monomerid = 35013   

TargetSerine/threonine-protein kinase pim-1(Homo sapiens (Human))
Abbott Laboratories

LigandPNGBDBM35013(benzothienopyrimidinone deriv., 13a)
Affinity DataKi:  5nM ΔG°:  -11.3kcal/moleT: 2°CAssay Description:In 384-well v-bottom polypropylene plates, compound (2% DMSO) was mixed with Pim kinase and peptide substrate, followed by immediate initiation with ...More data for this Ligand-Target Pair
In DepthDetails ArticlePubMed
TargetSerine/threonine-protein kinase pim-2(Homo sapiens (Human))
Abbott Laboratories

LigandPNGBDBM35013(benzothienopyrimidinone deriv., 13a)
Affinity DataKi:  30nM ΔG°:  -10.3kcal/moleT: 2°CAssay Description:In 384-well v-bottom polypropylene plates, compound (2% DMSO) was mixed with Pim kinase and peptide substrate, followed by immediate initiation with ...More data for this Ligand-Target Pair
In DepthDetails ArticlePubMed