BDBM351304 N-(4-bromo-3-chloro-2-fluorophenyl)-7- {[(3R,9aS)-hexahydro-1H-[1,4]oxazino[3,4- c][1,4]oxazin-3-ylmethyl]oxy}-6- (methyloxy)quinazolin-4-amine::US9796704, Entry 30

SMILES COc1cc2c(Nc3ccc(Br)c(Cl)c3F)ncnc2cc1OC[C@H]1CN2CCOCC2CO1

InChI Key InChIKey=CMTRUERFSJKMJQ-ARLHGKGLSA-N

Data  10 IC50

  Tab Delimited (TSV)   2D SDfile   Computed 3D by Vconf -m prep SDfile
Find this compound or compounds like it in BindingDB:
   Substructure
Similarity at least:  must be >=0.5
Exact match

Activity Spreadsheet -- Enzyme Inhibition Constant Data from BindingDB

Found 10 hits for monomerid = 351304   

TargetEphrin type-B receptor 4(Homo sapiens (Human))
Symphony Evolution

US Patent
LigandPNGBDBM351304(N-(4-bromo-3-chloro-2-fluorophenyl)-7- {[(3R,9aS)-...)
Affinity DataIC50: <50nMAssay Description:In AlphaScreen, when the donor and acceptor beads are close in proximity, a series of photochemical events will give rise to a fluorescent signal upo...More data for this Ligand-Target Pair
Ligand InfoPC cidPC sid
In DepthDetails US Patent
TargetEphrin type-A receptor 2(Homo sapiens (Human))
Symphony Evolution

US Patent
LigandPNGBDBM351304(N-(4-bromo-3-chloro-2-fluorophenyl)-7- {[(3R,9aS)-...)
Affinity DataIC50: <50nMAssay Description:In AlphaScreen, when the donor and acceptor beads are close in proximity, a series of photochemical events will give rise to a fluorescent signal upo...More data for this Ligand-Target Pair
Ligand InfoPC cidPC sid
In DepthDetails US Patent
TargetVascular endothelial growth factor receptor 2(Homo sapiens (Human))
Symphony Evolution

US Patent
LigandPNGBDBM351304(N-(4-bromo-3-chloro-2-fluorophenyl)-7- {[(3R,9aS)-...)
Affinity DataIC50: <50nMAssay Description:In AlphaScreen, when the donor and acceptor beads are close in proximity, a series of photochemical events will give rise to a fluorescent signal upo...More data for this Ligand-Target Pair
Ligand InfoPC cidPC sid
In DepthDetails US Patent
TargetVascular endothelial growth factor receptor 1(Homo sapiens (Human))
Symphony Evolution

US Patent
LigandPNGBDBM351304(N-(4-bromo-3-chloro-2-fluorophenyl)-7- {[(3R,9aS)-...)
Affinity DataIC50:  525nMAssay Description:In AlphaScreen, when the donor and acceptor beads are close in proximity, a series of photochemical events will give rise to a fluorescent signal upo...More data for this Ligand-Target Pair
Ligand InfoPC cidPC sid
In DepthDetails US Patent
TargetEpidermal growth factor receptor(Homo sapiens (Human))
Symphony Evolution

US Patent
LigandPNGBDBM351304(N-(4-bromo-3-chloro-2-fluorophenyl)-7- {[(3R,9aS)-...)
Affinity DataIC50: <50nMAssay Description:In AlphaScreen, when the donor and acceptor beads are close in proximity, a series of photochemical events will give rise to a fluorescent signal upo...More data for this Ligand-Target Pair
Ligand InfoPC cidPC sid
In DepthDetails US Patent
TargetReceptor tyrosine-protein kinase erbB-2(Homo sapiens (Human))
Symphony Evolution

US Patent
LigandPNGBDBM351304(N-(4-bromo-3-chloro-2-fluorophenyl)-7- {[(3R,9aS)-...)
Affinity DataIC50:  525nMAssay Description:In AlphaScreen, when the donor and acceptor beads are close in proximity, a series of photochemical events will give rise to a fluorescent signal upo...More data for this Ligand-Target Pair
Ligand InfoPC cidPC sid
In DepthDetails US Patent
TargetEphrin type-B receptor 4(Homo sapiens (Human))
Symphony Evolution

US Patent
LigandPNGBDBM351304(N-(4-bromo-3-chloro-2-fluorophenyl)-7- {[(3R,9aS)-...)
Affinity DataIC50:  525nMAssay Description:In AlphaScreen, when the donor and acceptor beads are close in proximity, a series of photochemical events will give rise to a fluorescent signal upo...More data for this Ligand-Target Pair
Ligand InfoPC cidPC sid
In DepthDetails US Patent
TargetEphrin type-A receptor 2(Homo sapiens (Human))
Symphony Evolution

US Patent
LigandPNGBDBM351304(N-(4-bromo-3-chloro-2-fluorophenyl)-7- {[(3R,9aS)-...)
Affinity DataIC50:  525nMAssay Description:In AlphaScreen, when the donor and acceptor beads are close in proximity, a series of photochemical events will give rise to a fluorescent signal upo...More data for this Ligand-Target Pair
Ligand InfoPC cidPC sid
In DepthDetails US Patent
TargetVascular endothelial growth factor receptor 2(Homo sapiens (Human))
Symphony Evolution

US Patent
LigandPNGBDBM351304(N-(4-bromo-3-chloro-2-fluorophenyl)-7- {[(3R,9aS)-...)
Affinity DataIC50:  525nMAssay Description:In AlphaScreen, when the donor and acceptor beads are close in proximity, a series of photochemical events will give rise to a fluorescent signal upo...More data for this Ligand-Target Pair
Ligand InfoPC cidPC sid
In DepthDetails US Patent
TargetEpidermal growth factor receptor(Homo sapiens (Human))
Symphony Evolution

US Patent
LigandPNGBDBM351304(N-(4-bromo-3-chloro-2-fluorophenyl)-7- {[(3R,9aS)-...)
Affinity DataIC50: <50nMAssay Description:In AlphaScreen, when the donor and acceptor beads are close in proximity, a series of photochemical events will give rise to a fluorescent signal upo...More data for this Ligand-Target Pair
Ligand InfoPC cidPC sid
In DepthDetails US Patent