BDBM351923 Preparation of 5-(2,4-di(8-oxa-3-azabicyclo[3.2.1]octan-3-yl)pyrido[2,3-d]pyrimidin-7-yl)-2-methoxyphenyl methanol ::US9796732, Compound 2

SMILES COc1ccc(cc1CO)-c1ccc2c(nc(nc2n1)N1CC2CCC(C1)O2)N1CC2CCC(C1)O2

InChI Key InChIKey=YNKVZRVOZBAZDZ-UHFFFAOYSA-N

Data  1 IC50

  Tab Delimited (TSV)   2D SDfile   Computed 3D by Vconf -m prep SDfile
Find this compound or compounds like it in BindingDB:
   Substructure
Similarity at least:  must be >=0.5
Exact match

Activity Spreadsheet -- Enzyme Inhibition Constant Data from BindingDB

Found 1 hit for monomerid = 351923   

TargetSerine/threonine-protein kinase mTOR(Homo sapiens (Human))
Shandong Luoxin Pharmaceutical Group Stock

US Patent
LigandPNGBDBM351923(Preparation of 5-(2,4-di(8-oxa-3-azabicyclo[3.2.1]...)
Affinity DataIC50:  3nMAssay Description:The test on activity against mTOR Kinase was performed using a 1.7 nM mTOR (Millipore, 14-770M), a 50 nM ULight-4EBP1 (Perkin-Elmer, TRF0128M) and a ...More data for this Ligand-Target Pair
Ligand InfoPC cidPC sid
In DepthDetails US Patent