BDBM35267 tripeptide-based inhibitor, 14j

SMILES CC(C)[C@H](NC(=O)CN1C(=O)N(CC(O)=O)C(=O)C1(C)C)C(=O)N1CCC[C@H]1C(=O)N[C@@H](C(C)C)C(=O)c1nc2ccccc2o1

InChI Key InChIKey=UFXGRDISHSOWGA-IGKWTDBASA-N

Data  1 IC50

  Tab Delimited (TSV)   2D SDfile   Computed 3D by Vconf -m prep SDfile
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Activity Spreadsheet -- Enzyme Inhibition Constant Data from BindingDB

Found 1 hit for monomerid = 35267   

TargetNeutrophil elastase(Homo sapiens (Human))
Dainippon Sumitomo Pharma

LigandPNGBDBM35267(tripeptide-based inhibitor, 14j)
Affinity DataIC50:  47nMpH: 7.5 T: 2°CAssay Description:To evaluate inhibitory effect of test compound, HNE was preincubated with each compound in the assay solution at 37 deg C for 4 min. The reaction was...More data for this Ligand-Target Pair
In DepthDetails ArticlePubMed