BDBM35414 5-oxidanylidene-N3-(oxolan-2-ylmethyl)-N8-pentyl-1-sulfanylidene-4H-[1,3]thiazolo[3,4-a]quinazoline-3,8-dicarboxamide::5-oxo-3-N-(oxolan-2-ylmethyl)-8-N-pentyl-1-sulfanylidene-4H-[1,3]thiazolo[3,4-a]quinazoline-3,8-dicarboxamide::5-oxo-N3-(2-oxolanylmethyl)-N8-pentyl-1-sulfanylidene-4H-thiazolo[3,4-a]quinazoline-3,8-dicarboxamide::5-oxo-N~8~-pentyl-N~3~-(tetrahydrofuran-2-ylmethyl)-1-thioxo-4,5-dihydro[1,3]thiazolo[3,4-a]quinazoline-3,8-dicarboxamide::MLS000094742::N'-amyl-5-keto-N-(tetrahydrofurfuryl)-1-thioxo-4H-thiazolo[3,4-a]quinazoline-3,8-dicarboxamide::SMR000030295::cid_3245487

SMILES CCCCCNC(=O)c1ccc2c(c1)n1c([nH]c2=O)c(sc1=S)C(=O)NCC1CCCO1

InChI Key InChIKey=SMIYUZPFDZKHFF-UHFFFAOYSA-N

Data  2 KI  11 IC50  1 EC50

  Tab Delimited (TSV)   2D SDfile   Computed 3D by Vconf -m prep SDfile
Find this compound or compounds like it in BindingDB:
   Substructure
Similarity at least:  must be >=0.5
Exact match

Activity Spreadsheet -- Enzyme Inhibition Constant Data from BindingDB

Found 14 hits for monomerid = 35414   

TargetfMet-Leu-Phe receptor(Homo sapiens (Human))
Nmmlsc

Curated by PubChem BioAssay
LigandPNGBDBM35414(5-oxidanylidene-N3-(oxolan-2-ylmethyl)-N8-pentyl-1...)
Affinity DataKi:  2.66E+4nMAssay Description:University of New Mexico Assay Overview: Assay Support: NIH 1R03MH076381-01 Assay for Formylpeptide Receptor Family Ligands PI: Bruce S. Edwards, Ph...More data for this Ligand-Target Pair
In DepthDetails PCBioAssay
TargetN-formyl peptide receptor 2(Homo sapiens (Human))
Nmmlsc

Curated by PubChem BioAssay
LigandPNGBDBM35414(5-oxidanylidene-N3-(oxolan-2-ylmethyl)-N8-pentyl-1...)
Affinity DataKi: >4.03E+4nMAssay Description:University of New Mexico Assay Overview Assay Support: NIH 1R03MH076381-01 Assay for Formylpeptide Receptor Family Ligands PI: Bruce S. Edwards, Ph....More data for this Ligand-Target Pair
In DepthDetails PCBioAssay
TargetfMet-Leu-Phe receptor(Homo sapiens (Human))
Nmmlsc

Curated by PubChem BioAssay
LigandPNGBDBM35414(5-oxidanylidene-N3-(oxolan-2-ylmethyl)-N8-pentyl-1...)
Affinity DataIC50:  4.07E+4nMAssay Description:University of New Mexico Assay Overview: Assay Support: NIH 1R03MH076381-01 Assay for Formylpeptide Receptor Family Ligands PI: Bruce S. Edwards, Ph...More data for this Ligand-Target Pair
In DepthDetails PCBioAssay
TargetDual specificity protein phosphatase 1(Homo sapiens (Human))
University Of Pittsburgh

Curated by PubChem BioAssay
LigandPNGBDBM35414(5-oxidanylidene-N3-(oxolan-2-ylmethyl)-N8-pentyl-1...)
Affinity DataIC50:  3.67E+4nMAssay Description:The MKP-1 dose response Active/Probe assessment-Catalase assay has been developed to evaluate the effects of adding 100 U/mL of Catalase on the MKP-1...More data for this Ligand-Target Pair
In DepthDetails PCBioAssay
TargetDual specificity protein phosphatase 1(Homo sapiens (Human))
University Of Pittsburgh

Curated by PubChem BioAssay
LigandPNGBDBM35414(5-oxidanylidene-N3-(oxolan-2-ylmethyl)-N8-pentyl-1...)
Affinity DataIC50:  3.70E+4nMAssay Description:The MKP-1 dose response assay Active/Probe Assessment Assay - Reproducibility testing has been developed to test the reproducibility of MKP-1 inhibit...More data for this Ligand-Target Pair
In DepthDetails PCBioAssay
TargetDual specificity protein phosphatase 6(Rattus norvegicus)
University Of Pittsburgh

Curated by PubChem BioAssay
LigandPNGBDBM35414(5-oxidanylidene-N3-(oxolan-2-ylmethyl)-N8-pentyl-1...)
Affinity DataIC50: >5.00E+4nMAssay Description:The in vitro MKP-3 Phosphatase dose response hit/probe assessment assay has been developed and run at the University of Pittsburgh Molecular Screenin...More data for this Ligand-Target Pair
In DepthDetails PCBioAssay
TargetDual specificity protein phosphatase 6(Rattus norvegicus)
University Of Pittsburgh

Curated by PubChem BioAssay
LigandPNGBDBM35414(5-oxidanylidene-N3-(oxolan-2-ylmethyl)-N8-pentyl-1...)
Affinity DataIC50: >5.00E+4nMAssay Description:The MKP-3 dose response Active/Probe assessment-Catalase assay has been developed to evaluate the effects of adding 100 U/mL of Catalase on the MKP-3...More data for this Ligand-Target Pair
In DepthDetails PCBioAssay
TargetDual specificity protein phosphatase 6(Rattus norvegicus)
University Of Pittsburgh

Curated by PubChem BioAssay
LigandPNGBDBM35414(5-oxidanylidene-N3-(oxolan-2-ylmethyl)-N8-pentyl-1...)
Affinity DataIC50: >5.00E+4nMAssay Description:The MKP-3 dose response assay Active/Probe Assessment Assay - Reproducibility testing has been developed to test the reproducibility of MKP-3 inhibit...More data for this Ligand-Target Pair
In DepthDetails PCBioAssay
TargetM-phase inducer phosphatase 2(Homo sapiens (Human))
University Of Pittsburgh

Curated by PubChem BioAssay
LigandPNGBDBM35414(5-oxidanylidene-N3-(oxolan-2-ylmethyl)-N8-pentyl-1...)
Affinity DataIC50: >5.00E+4nMAssay Description:The MKP-1 Dual Specificity Protein Tyrosine Phosphatase Probe Assessment Cdc25B Dose Response Selectivity Assay has been developed to evaluate the PT...More data for this Ligand-Target Pair
In DepthDetails PCBioAssay
TargetM1 family aminopeptidase(Plasmodium falciparum (isolate FcB1 / Columbia))
Srmlsc

Curated by PubChem BioAssay
LigandPNGBDBM35414(5-oxidanylidene-N3-(oxolan-2-ylmethyl)-N8-pentyl-1...)
Affinity DataIC50:  3.70E+4nMAssay Description:Southern Research Molecular Libraries Screening Center (SRMLSC) Southern Research Institute (Birmingham, Alabama) NIH Molecular Libraries Screening...More data for this Ligand-Target Pair
In DepthDetails PCBioAssay
TargetStreptokinase A(Streptococcus pyogenes M1 GAS)
Broad Institute

Curated by PubChem BioAssay
LigandPNGBDBM35414(5-oxidanylidene-N3-(oxolan-2-ylmethyl)-N8-pentyl-1...)
Affinity DataEC50:  2.11E+4nMAssay Description:Keywords: Group A streptococcus, GAS, streptokinase, expression, virulence, inhibition, dose response, EC50 Assay Overview: The goal of this assa...More data for this Ligand-Target Pair
In DepthDetails PCBioAssay
TargetDual specificity protein phosphatase 1(Homo sapiens (Human))
University Of Pittsburgh

Curated by PubChem BioAssay
LigandPNGBDBM35414(5-oxidanylidene-N3-(oxolan-2-ylmethyl)-N8-pentyl-1...)
Affinity DataIC50:  3.67E+4nMAssay Description:The MKP-1 dose response Active/Probe assessment-DTT assay has been developed to evaluate the effects of increased DTT concentration on the MKP-1 inhi...More data for this Ligand-Target Pair
In DepthDetails PCBioAssay
TargetDual specificity protein phosphatase 1(Homo sapiens (Human))
University Of Pittsburgh

Curated by PubChem BioAssay
LigandPNGBDBM35414(5-oxidanylidene-N3-(oxolan-2-ylmethyl)-N8-pentyl-1...)
Affinity DataIC50:  3.84E+4nMpH: 7.0 T: 2°CAssay Description:The MKP-1 HTS confirmation dose response assay has been developed to confirm actives identified in the MH-76391 In vitro HTS assay for MKP-1 inhibito...More data for this Ligand-Target Pair
In DepthDetails PCBioAssay
TargetN-formyl peptide receptor 2(Homo sapiens (Human))
Nmmlsc

Curated by PubChem BioAssay
LigandPNGBDBM35414(5-oxidanylidene-N3-(oxolan-2-ylmethyl)-N8-pentyl-1...)
Affinity DataIC50: >6.67E+4nMAssay Description:University of New Mexico Assay Overview Assay Support: NIH 1R03MH076381-01 Assay for Formylpeptide Receptor Family Ligands PI: Bruce S. Edwards, Ph....More data for this Ligand-Target Pair
In DepthDetails PCBioAssay