BDBM355830 US9815836, Compound 15
SMILES O=C1NCCS(=O)(=O)CCCn2cc(cn2)-c2cccc(n2)C(=O)Nc2cn(nc12)C1CCOCC1
InChI Key InChIKey=WNIHRLHFZDFIJN-UHFFFAOYSA-N
Data 2 IC50
Activity Spreadsheet -- Enzyme Inhibition Constant Data from BindingDB
Found 2 hits for monomerid = 355830
Affinity DataIC50: <100nMAssay Description:IRAK4 is a human purified recombinant enzyme (His-TEV-IRAK4 (1-460)).In this assay, IRAK4 hydrolyses ATP, autophosphorylates and phosphorylates a Ser...More data for this Ligand-Target Pair
TargetInterleukin-1 receptor-associated kinase 1 [194-712](Homo sapiens (Human))
Merck Patent
US Patent
Merck Patent
US Patent
Affinity DataIC50: 550nMAssay Description:IRAK1 is a human purified recombinant enzyme (His-TEV-IRAK1 (194-712))In this assay, IRAK1 hydrolyses ATP and autophosphorylates. Measurement of IRAK...More data for this Ligand-Target Pair