BDBM356078 2-fluoro-5-(1-methyl-1H- pyrazol-3-yl)-N-(6-((1- methylureido)methyl)-2- phenylpyridin-3-yl)-4- (trifluoromethyl)benzamide::US9815846, Compound 78

SMILES CN(Cc1ccc(NC(=O)c2cc(-c3ccn(C)n3)c(cc2F)C(F)(F)F)c(n1)-c1ccccc1)C(N)=O

InChI Key InChIKey=DQTVFEJWTCTUHL-UHFFFAOYSA-N

Data  1 IC50

  Tab Delimited (TSV)   2D SDfile   Computed 3D by Vconf -m prep SDfile
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Activity Spreadsheet -- Enzyme Inhibition Constant Data from BindingDB

Found 1 hit for monomerid = 356078   

TargetHigh affinity nerve growth factor receptor(Homo sapiens (Human))
Merck Sharp & Dohme

US Patent
LigandPNGBDBM356078(2-fluoro-5-(1-methyl-1H- pyrazol-3-yl)-N-(6-((1- m...)
Affinity DataIC50:  1.10nMAssay Description:TrkA functional activity was measured using a DiscoverX PathHunter assay. In this assay, U2OS cells express the human TrkA receptor as a fusion with ...More data for this Ligand-Target Pair
Ligand InfoPC cidPC sid
In DepthDetails US Patent