BDBM356146 2-fluoro-N-(2-phenyl-5,6,7,8- tetrahydro-1,6-naphthyridin-3- yl)-5-(pyridin-2-yl)-4- (trifluoromethyl)benzamide::US9815846, Compound 146

SMILES Fc1cc(c(cc1C(=O)Nc1cc2CNCCc2nc1-c1ccccc1)-c1ccccn1)C(F)(F)F

InChI Key InChIKey=MZVNKKLFPVLAEH-UHFFFAOYSA-N

Data  1 IC50

  Tab Delimited (TSV)   2D SDfile   Computed 3D by Vconf -m prep SDfile
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Activity Spreadsheet -- Enzyme Inhibition Constant Data from BindingDB

Found 1 hit for monomerid = 356146   

TargetHigh affinity nerve growth factor receptor(Homo sapiens (Human))
Merck Sharp & Dohme

US Patent
LigandPNGBDBM356146(2-fluoro-N-(2-phenyl-5,6,7,8- tetrahydro-1,6-napht...)
Affinity DataIC50:  13nMAssay Description:TrkA functional activity was measured using a DiscoverX PathHunter assay. In this assay, U2OS cells express the human TrkA receptor as a fusion with ...More data for this Ligand-Target Pair
Ligand InfoPC cidPC sid
In DepthDetails US Patent