BDBM358081 ((2S,4R)-2-(3-(4-amino-5-(1-(tetrahydro-2H- pyran-4-yl)-1H-pyrazol-5-yl)pyrrolo[2,1-f][1,2,4] triazin-7-yl)phenyl)-4-hydroxypyrrolidin-1- yl)(pyridin-3-yl)methanone::US10214537, Example 150
SMILES CC(C)[C@@H]1C[C@@H](O)CN1C(=O)c1cccnc1
InChI Key InChIKey=UBUUNFPGICHHNJ-NEPJUHHUSA-N
Data 1 IC50
Activity Spreadsheet -- Enzyme Inhibition Constant Data from BindingDB
Found 1 hit for monomerid = 358081
TargetPhosphatidylinositol 4,5-bisphosphate 3-kinase catalytic subunit delta isoform(Homo sapiens (Human))
Bristol-Myers Squibb
US Patent
Bristol-Myers Squibb
US Patent
Affinity DataIC50: 3nMAssay Description:The ADP-Glo format PI3K assays were performed in Proxiplate 384-well plates (Perkin Elmer #6008280). The final assay volume was 2 μl prepared fr...More data for this Ligand-Target Pair