BDBM358557 4-acetyl-1-(5-(4-amino-5-(1- cyclopropyl-1H-pyrazol-4-yl)pyrrolo [2,1-f][1,2,4]triazin-7-yl)-2- fluorophenyl)-3,3-dimethyl-5,5,6,6- tetradeuteropiperazin-2-one::US10214537, Example 634
SMILES CC(=O)N1CCN(C(=O)C1(C)C)c1cc(ccc1F)-c1cc(-c2cnn(c2)C2CC2)c2c(N)ncnn12
InChI Key InChIKey=OMADCHKSAMFDAG-UHFFFAOYSA-N
Data 1 IC50
Activity Spreadsheet -- Enzyme Inhibition Constant Data from BindingDB
Found 1 hit for monomerid = 358557
TargetPhosphatidylinositol 4,5-bisphosphate 3-kinase catalytic subunit delta isoform(Homo sapiens (Human))
Bristol-Myers Squibb
US Patent
Bristol-Myers Squibb
US Patent
Affinity DataIC50: 2nMAssay Description:The ADP-Glo format PI3K assays were performed in Proxiplate 384-well plates (Perkin Elmer #6008280). The final assay volume was 2 μl prepared fr...More data for this Ligand-Target Pair