BDBM3601 4-[(3-Bromophenyl)amino]-6-chloropyrido[3,4-d]pyrimidine::CHEMBL296377::N-(3-bromophenyl)-6-chloropyrido[3,4-d]pyrimidin-4-amine::Pyrido[3,4-d]pyrimidine 7d

SMILES Clc1cc2c(Nc3cccc(Br)c3)ncnc2cn1

InChI Key InChIKey=APXDAYLGZSXVDB-UHFFFAOYSA-N

Data  2 IC50

  Tab Delimited (TSV)   2D SDfile   Computed 3D by Vconf -m prep SDfile
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Activity Spreadsheet -- Enzyme Inhibition Constant Data from BindingDB

Found 2 hits for monomerid = 3601   

TargetEpidermal growth factor receptor(Homo sapiens (Human))
University Of Zurich

Curated by ChEMBL
LigandPNGBDBM3601(4-[(3-Bromophenyl)amino]-6-chloropyrido[3,4-d]pyri...)
Affinity DataIC50:  41nMAssay Description:Inhibition of EGFRMore data for this Ligand-Target Pair
In DepthDetails ArticlePubMed
TargetEpidermal growth factor receptor(Homo sapiens (Human))
University Of Zurich

Curated by ChEMBL
LigandPNGBDBM3601(4-[(3-Bromophenyl)amino]-6-chloropyrido[3,4-d]pyri...)
Affinity DataIC50:  40nMpH: 7.4 T: 2°CAssay Description:IC50 is the inhibitor concentration which inhibits 50% of kinase activity that catalyzes the transfer of the terminal phosphate from [gamma-32P] labe...More data for this Ligand-Target Pair
In DepthDetails ArticlePubMed