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BDBM365921 ({2,6-dimethoxy-4-[(2-methyl-3- phenylphenyl)methoxy]phenyl} methyl)[3-(1H-imidazol-1- yl)propyl]amine::US9872852, Example 173

SMILES: COc1cc(OCc2cccc(c2C)-c2ccccc2)cc(OC)c1CNCCCn1ccnc1

InChI Key: InChIKey=YJJMLDZYDIHRJF-UHFFFAOYSA-N

Data: 1 IC50

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Activity Spreadsheet -- Enzyme Inhibition Constant Data from BindingDB

Found 1 hit for monomerid = 365921   
Target/Host
(Institution)
LigandTarget/Host
Links
Ligand
Links
Trg + Lig
Links
Ki
nM
ΔG°
kcal/mole
IC50
nM
Kd
nM
EC50
nM
koff
s-1
kon
M-1s-1
pHTemp
°C
Programmed cell death 1 ligand 1


(Homo sapiens (Human))
BDBM365921
PNG
(({2,6-dimethoxy-4-[(2-methyl-3- phenylphenyl)metho...)
Show SMILES COc1cc(OCc2cccc(c2C)-c2ccccc2)cc(OC)c1CNCCCn1ccnc1
Show InChI InChI=1S/C29H33N3O3/c1-22-24(11-7-12-26(22)23-9-5-4-6-10-23)20-35-25-17-28(33-2)27(29(18-25)34-3)19-30-13-8-15-32-16-14-31-21-32/h4-7,9-12,14,16-18,21,30H,8,13,15,19-20H2,1-3H3
PDB

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PC cid
PC sid
UniChem
US Patent
n/an/a 53n/an/an/an/an/an/a



Bristol-Myers Squibb Co.

US Patent


Assay Description
All binding studies were performed in an HTRF assay buffer consisting of dPBS supplemented with 0.1% (withv) bovine serum albumin and 0.05% (v/v) Twe...


US Patent US9872852 (2018)


BindingDB Entry DOI: 10.7270/Q2RN3B42
More data for this
Ligand-Target Pair