BDBM36811 BMS614

SMILES CC1(C)CC=C(c2cnc3ccccc3c2)c2cc(ccc12)C(=O)Nc1ccc(cc1)C(O)=O

InChI Key InChIKey=WGLMBRZXZDAQHP-UHFFFAOYSA-N

Data  2 KI

  Tab Delimited (TSV)   2D SDfile   Computed 3D by Vconf -m prep SDfile
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Activity Spreadsheet -- Enzyme Inhibition Constant Data from BindingDB

Found 2 hits for monomerid = 36811   

TargetRetinoic acid receptor alpha [200-419]/gamma [183-417](Homo sapiens (Human))
Institute of Genetics and Molecular and Cellular Biology (IGBMC)

LigandPNGBDBM36811(BMS614)
Affinity DataKi:  1nM ΔG°:  -11.4kcal/molepH: 8.0 T: 2°CAssay Description:Competitive assay were perform with 5nM tritiated all-trans retinoic acid (t-RA; 5nM) with or without 100-fold excess of non-radioactive t-RA (500nM)...More data for this Ligand-Target Pair
In DepthDetails ArticlePubMed
TargetRetinoic acid receptor alpha [200-419](Homo sapiens (Human))
Institute of Genetics and Molecular and Cellular Biology (IGBMC)

LigandPNGBDBM36811(BMS614)
Affinity DataKi:  2.5nM ΔG°:  -10.9kcal/molepH: 8.0 T: 2°CAssay Description:Competitive assay were perform with 5nM tritiated all-trans retinoic acid (t-RA; 5nM) with or without 100-fold excess of non-radioactive t-RA (500nM)...More data for this Ligand-Target Pair
In DepthDetails ArticlePubMedMMDB