BDBM368244 US10227338, Example 26

SMILES CN[C@@H]1CCCN(C1)c1cc(F)ccc1Nc1cc(F)c(cc1Cl)S(=O)(=O)Nc1cscn1

InChI Key InChIKey=GYEUCDRCAZSBHR-CQSZACIVSA-N

Data  2 IC50

  Tab Delimited (TSV)   2D SDfile   Computed 3D by Vconf -m prep SDfile
Find this compound or compounds like it in BindingDB:
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Exact match

Activity Spreadsheet -- Enzyme Inhibition Constant Data from BindingDB

Found 2 hits for monomerid = 368244   

TargetSodium channel protein type 5 subunit alpha(Homo sapiens (Human))
Daewoong Pharmaceutical

US Patent
LigandPNGBDBM368244(US10227338, Example 26)
Affinity DataIC50: >1.00E+4nMAssay Description:In order to measure the sodium ion channel blocking effect, an IonFlux16 Auto patch clamp system (Fluxion, Inc.) and a plate for exclusive use were u...More data for this Ligand-Target Pair
Ligand InfoPC cidPC sid
In DepthDetails US Patent
TargetSodium channel protein type 9 subunit alpha(Homo sapiens (Human))
Daewoong Pharmaceutical

US Patent
LigandPNGBDBM368244(US10227338, Example 26)
Affinity DataIC50:  66nMAssay Description:In order to measure the sodium ion channel blocking effect, an IonFlux16 Auto patch clamp system (Fluxion, Inc.) and a plate for exclusive use were u...More data for this Ligand-Target Pair
Ligand InfoPC cidPC sid
In DepthDetails US Patent