BDBM370815 US10239835, Example 00366::US20240199576, Example 10 from WO 2016/049165
SMILES [H][C@@]1(C[C@]2([H])CN(C[C@H](O)c3ccc(O)cn3)C[C@]2([H])C1)Oc1ccccc1F
InChI Key InChIKey=NEFQLCKWVRZEJA-ZDXGLAPJSA-N
Data 2 IC50
Activity Spreadsheet -- Enzyme Inhibition Constant Data from BindingDB
Found 2 hits for monomerid = 370815
Affinity DataIC50: 2.30E+3nMAssay Description:hERG currents were recorded using the Qpatch automated patch clamp systems (Sophion Bioscience Inc., North Brunswick, NJ) in the whole (single) cell ...More data for this Ligand-Target Pair
Affinity DataIC50: 8.30nMAssay Description:Cell Culture and plating: HEK293 cells expressing NR1/NR2B (Chantest, Cleveland, Ohio) were grown to 70-80% confluency as an adherent monolayer in st...More data for this Ligand-Target Pair