BindingDB logo
myBDB logout

BDBM373261 FD-2013027::US9902709, Compound Example 5

SMILES: Cc1c(Oc2ccc(NC(=O)Nc3ccc(Cl)c(c3)C(F)(F)F)cc2)ccnc1-c1cnn(C)c1

InChI Key: InChIKey=QMTYMFAGVZGZBJ-UHFFFAOYSA-N

Data: 1 IC50

Find this compound or compounds like it in BindingDB or PDB:
   Substructure
Similarity at least:  must be >=0.5
Exact match

Activity Spreadsheet -- Enzyme Inhibition Constant Data from BindingDB

Found 1 hit for monomerid = 373261   
Target/Host
(Institution)
LigandTarget/Host
Links
Ligand
Links
Trg + Lig
Links
Ki
nM
ΔG°
kcal/mole
IC50
nM
Kd
nM
EC50/IC50
nM
koff
s-1
kon
M-1s-1
pHTemp
°C
Vascular endothelial growth factor receptor 2


(Homo sapiens (Human))
BDBM373261
PNG
(FD-2013027 | US9902709, Compound Example 5)
Show SMILES Cc1c(Oc2ccc(NC(=O)Nc3ccc(Cl)c(c3)C(F)(F)F)cc2)ccnc1-c1cnn(C)c1
Show InChI InChI=1S/C24H19ClF3N5O2/c1-14-21(9-10-29-22(14)15-12-30-33(2)13-15)35-18-6-3-16(4-7-18)31-23(34)32-17-5-8-20(25)19(11-17)24(26,27)28/h3-13H,1-2H3,(H2,31,32,34)
PDB
MMDB

NCI pathway
Reactome pathway
KEGG

UniProtKB/SwissProt

B.MOAD
DrugBank
antibodypedia
GoogleScholar
PC cid
PC sid
UniChem
US Patent
n/an/a 317n/an/an/an/an/an/a



PEKING UNIVERSITY FOUNDER GROUP CO., LTD.

US Patent


Assay Description
Kinase Enzymatic step assay Control (10 μL) Sample Negative Positive Compound 4 μL 4 μL 2.5% 4 μL 2.5% DMSO/kinase DMSO/kinase bu...


US Patent US9902709 (2018)


BindingDB Entry DOI: 10.7270/Q2T43WF5
More data for this
Ligand-Target Pair