BDBM37633 (2S)-2-amino-3-(4-hydroxy-3-iodo-phenyl)propionic acid::(2S)-2-amino-3-(4-hydroxy-3-iodophenyl)propanoic acid::(2S)-2-azanyl-3-(3-iodanyl-4-oxidanyl-phenyl)propanoic acid::3-IODO-L-TYROSINE::3-Iodo-L-tyrosine (I-Tyr)::MLS000069664::Monoiodotyrosine::SMR000059143::cid_439744

SMILES N[C@@H](Cc1ccc(O)c(I)c1)C(O)=O

InChI Key InChIKey=UQTZMGFTRHFAAM-ZETCQYMHSA-N

Data  2 KI  4 IC50  2 Kd

PDB links: 31 PDB IDs match this monomer.

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Activity Spreadsheet -- Enzyme Inhibition Constant Data from BindingDB

Found 8 hits for monomerid = 37633   

TargetN-formyl peptide receptor 2(Homo sapiens (Human))
Nmmlsc

Curated by PubChem BioAssay
LigandPNGBDBM37633((2S)-2-amino-3-(4-hydroxy-3-iodo-phenyl)propionic ...)
Affinity DataKi: >4.03E+4nMAssay Description:University of New Mexico Assay Overview Assay Support: NIH 1R03MH076381-01 Assay for Formylpeptide Receptor Family Ligands PI: Bruce S. Edwards, Ph....More data for this Ligand-Target Pair
In DepthDetails PCBioAssay
TargetfMet-Leu-Phe receptor(Homo sapiens (Human))
Nmmlsc

Curated by PubChem BioAssay
LigandPNGBDBM37633((2S)-2-amino-3-(4-hydroxy-3-iodo-phenyl)propionic ...)
Affinity DataKi: >4.37E+4nMAssay Description:University of New Mexico Assay Overview: Assay Support: NIH 1R03MH076381-01 Assay for Formylpeptide Receptor Family Ligands PI: Bruce S. Edwards, Ph...More data for this Ligand-Target Pair
In DepthDetails PCBioAssay
TargetIodotyrosine deiodinase 1 [1-1,32-289](Homo sapiens (Human))
Johns Hopkins University

LigandPNGBDBM37633((2S)-2-amino-3-(4-hydroxy-3-iodo-phenyl)propionic ...)
Affinity DataKd:  90nMAssay Description:Dissociation constants (Kd) for the ligands of IYD were determined by their ability to quench the fluorescence of the oxidized FMN (FMNox) (λex ...More data for this Ligand-Target Pair
TargetIodotyrosine deiodinase [1-228](Haliscomenobacter hydrossis)
Johns Hopkins University

LigandPNGBDBM37633((2S)-2-amino-3-(4-hydroxy-3-iodo-phenyl)propionic ...)
Affinity DataKd:  8.20E+3nMAssay Description:Dissociation constants (Kd) for the ligands of IYD were determined by their ability to quench the fluorescence of the oxidized FMN (FMNox) (λex ...More data for this Ligand-Target Pair
TargetTyrosine 3-monooxygenase(Rattus norvegicus)
Pfizer

Curated by ChEMBL
LigandPNGBDBM37633((2S)-2-amino-3-(4-hydroxy-3-iodo-phenyl)propionic ...)
Affinity DataIC50:  1.40nMAssay Description:Inhibition of rat tyrosine hydroxylaseMore data for this Ligand-Target Pair
In DepthDetails ArticlePubMed
TargetN-formyl peptide receptor 2(Homo sapiens (Human))
Nmmlsc

Curated by PubChem BioAssay
LigandPNGBDBM37633((2S)-2-amino-3-(4-hydroxy-3-iodo-phenyl)propionic ...)
Affinity DataIC50: >6.67E+4nMAssay Description:University of New Mexico Assay Overview Assay Support: NIH 1R03MH076381-01 Assay for Formylpeptide Receptor Family Ligands PI: Bruce S. Edwards, Ph....More data for this Ligand-Target Pair
In DepthDetails PCBioAssay
TargetfMet-Leu-Phe receptor(Homo sapiens (Human))
Nmmlsc

Curated by PubChem BioAssay
LigandPNGBDBM37633((2S)-2-amino-3-(4-hydroxy-3-iodo-phenyl)propionic ...)
Affinity DataIC50: >6.67E+4nMAssay Description:University of New Mexico Assay Overview: Assay Support: NIH 1R03MH076381-01 Assay for Formylpeptide Receptor Family Ligands PI: Bruce S. Edwards, Ph...More data for this Ligand-Target Pair
In DepthDetails PCBioAssay
TargetGenome polyprotein(West Nile virus)
University Of Pittsburgh

Curated by PubChem BioAssay
LigandPNGBDBM37633((2S)-2-amino-3-(4-hydroxy-3-iodo-phenyl)propionic ...)
Affinity DataIC50: >5.00E+4nMAssay Description:The HTS assay to identify Inhibitors of West Nile Virus (WNV) NS2bNS3 Proteinase was proposed by Dr Alex Strongin of the Burnham Institute XO1-MH0776...More data for this Ligand-Target Pair
In DepthDetails PCBioAssay