BDBM378804 N-(1-((1-(3-chlorobenzyl)-1H-pyrazol-4-yl)methyl)azetidin-3-yl)-1-cyclopropyl-1H-1,2,3-triazole-4-carboxamide::US10266526, Compound 987

SMILES Clc1cccc(Cn2cc(CN3CC(C3)NC(=O)c3cn(nn3)C3CC3)cn2)c1

InChI Key InChIKey=JWUZDJIRXQOWOM-UHFFFAOYSA-N

Data  1 IC50

  Tab Delimited (TSV)   2D SDfile   Computed 3D by Vconf -m prep SDfile
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   Substructure
Similarity at least:  must be >=0.5
Exact match

Activity Spreadsheet -- Enzyme Inhibition Constant Data from BindingDB

Found 1 hit for monomerid = 378804   

TargetN-lysine methyltransferase SMYD2(Homo sapiens (Human))
Epizyme

US Patent
LigandPNGBDBM378804(N-(1-((1-(3-chlorobenzyl)-1H-pyrazol-4-yl)methyl)a...)
Affinity DataIC50:  24nMAssay Description:The assays were all performed in a buffer consisting of 20 mM Bicine (pH=7.6), 1 mM TCEP, 0.005% Bovine Skin Gelatin, and 0.002% Tween20, prepared on...More data for this Ligand-Target Pair
Ligand InfoPC cidPC sid
In DepthDetails US Patent