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BDBM37963 2-(2-((2-((4-(((1,1,1,3,3,3-Hexafluoropropan-2- yl)oxy)carbonyl)piperazin-1-yl)methyl)-5- (trifluoromethyl)phenyl)amino)ethoxy)acetic acid::US10093635, Example 9

SMILES: OC(=O)COCCNc1cc(ccc1CN1CCN(CC1)C(=O)OC(C(F)(F)F)C(F)(F)F)C(F)(F)F

InChI Key: InChIKey=MBLVCNOEBHFLLS-UHFFFAOYSA-N

Data: 1 IC50

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Activity Spreadsheet -- Enzyme Inhibition Constant Data from BindingDB

Found 1 hit for monomerid = 37963   
Target/Host
(Institution)
LigandTarget/Host
Links
Ligand
Links
Trg + Lig
Links
Ki
nM
ΔG°
kcal/mole
IC50
nM
Kd
nM
EC50
nM
koff
s-1
kon
M-1s-1
pHTemp
°C
Monoglyceride lipase


(Homo sapiens (Human))
BDBM37963
PNG
(2-(2-((2-((4-(((1,1,1,3,3,3-Hexafluoropropan-2- yl...)
Show SMILES OC(=O)COCCNc1cc(ccc1CN1CCN(CC1)C(=O)OC(C(F)(F)F)C(F)(F)F)C(F)(F)F
Show InChI InChI=1S/C14H13N5OS/c1-9(13(20)18-11-5-3-2-4-6-11)21-14-17-8-10(7-15)12(16)19-14/h2-6,8-9H,1H3,(H,18,20)(H2,16,17,19)
PDB
MMDB

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PC sid
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Similars

US Patent
n/an/a 5.50E+3n/an/an/an/an/a25



ABIDE THERAPEUTICS, INC.

US Patent


Assay Description
Proteomes (human prefrontal cortex or cell membrane fractions) (50 μL, 1.0-2.0 mg/mL total protein concentration) were preincubated with varying...


US Patent US10093635 (2018)


BindingDB Entry DOI: 10.7270/Q2FF3VD0
More data for this
Ligand-Target Pair