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BDBM37980 1-(2-((4-(((1,1,1,3,3,3-Hexafluoropropan-2- yl)oxy)carbonyl)piperazin-1-yl)methyl)-6- (trifluoromethyl)phenoxy)cyclopropane-1- carboxylic acid::US10093635, Example 22

SMILES: OC(=O)C1(CC1)Oc1c(CN2CCN(CC2)C(=O)OC(C(F)(F)F)C(F)(F)F)cccc1C(F)(F)F

InChI Key: InChIKey=RTGHFSIIZIJGNZ-UHFFFAOYSA-N

Data: 1 IC50

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Activity Spreadsheet -- Enzyme Inhibition Constant Data from BindingDB

Found 1 hit for monomerid = 37980   
Target/Host
(Institution)
LigandTarget/Host
Links
Ligand
Links
Trg + Lig
Links
Ki
nM
ΔG°
kcal/mole
IC50
nM
Kd
nM
EC50
nM
koff
s-1
kon
M-1s-1
pHTemp
°C
Monoglyceride lipase


(Homo sapiens (Human))
BDBM37980
PNG
(1-(2-((4-(((1,1,1,3,3,3-Hexafluoropropan-2- yl)oxy...)
Show SMILES OC(=O)C1(CC1)Oc1c(CN2CCN(CC2)C(=O)OC(C(F)(F)F)C(F)(F)F)cccc1C(F)(F)F
Show InChI InChI=1S/C16H24N2O4S2/c1-3-5-11-23(19,20)16(24(21,22)12-6-4-2)15-17-13-9-7-8-10-14(13)18-15/h7-10,16H,3-6,11-12H2,1-2H3,(H,17,18)
PDB
MMDB

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Similars

US Patent
n/an/a 5.50E+3n/an/an/an/an/a25



ABIDE THERAPEUTICS, INC.

US Patent


Assay Description
Proteomes (human prefrontal cortex or cell membrane fractions) (50 μL, 1.0-2.0 mg/mL total protein concentration) were preincubated with varying...


US Patent US10093635 (2018)


BindingDB Entry DOI: 10.7270/Q2FF3VD0
More data for this
Ligand-Target Pair