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BDBM37986 1-((3-((4-(((1,1,1,3,3,3-hexafluoropropan-2- yl)oxy)carbonyl)piperazin-1-yl)methyl)-5- (trifluoromethyl)phenoxy)methyl) cyclopropane-1-carboxylic acid::US10093635, Example 28

SMILES: OC(=O)C1(COc2cc(CN3CCN(CC3)C(=O)OC(C(F)(F)F)C(F)(F)F)cc(c2)C(F)(F)F)CC1

InChI Key: InChIKey=RAUNTNYNYHVWLH-UHFFFAOYSA-N

Data: 1 IC50

Find this compound or compounds like it in BindingDB or PDB:
   Substructure
Similarity at least:  must be >=0.5
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Activity Spreadsheet -- Enzyme Inhibition Constant Data from BindingDB

Found 1 hit for monomerid = 37986   
Target/Host
(Institution)
LigandTarget/Host
Links
Ligand
Links
Trg + Lig
Links
Ki
nM
ΔG°
kcal/mole
IC50
nM
Kd
nM
EC50
nM
koff
s-1
kon
M-1s-1
pHTemp
°C
Monoglyceride lipase


(Homo sapiens (Human))
BDBM37986
PNG
(1-((3-((4-(((1,1,1,3,3,3-hexafluoropropan-2- yl)ox...)
Show SMILES OC(=O)C1(COc2cc(CN3CCN(CC3)C(=O)OC(C(F)(F)F)C(F)(F)F)cc(c2)C(F)(F)F)CC1
Show InChI InChI=1S/C13H10N6OS/c1-19(12(20)10-8-15-5-6-16-10)13-18-17-11(21-13)9-3-2-4-14-7-9/h2-8H,1H3
PDB
MMDB

Reactome pathway
KEGG

UniProtKB/SwissProt

B.MOAD
antibodypedia
GoogleScholar
PC cid
PC sid
UniChem
US Patent
n/an/a 5.50E+3n/an/an/an/an/a25



ABIDE THERAPEUTICS, INC.

US Patent


Assay Description
Proteomes (human prefrontal cortex or cell membrane fractions) (50 μL, 1.0-2.0 mg/mL total protein concentration) were preincubated with varying...


US Patent US10093635 (2018)


BindingDB Entry DOI: 10.7270/Q2FF3VD0
More data for this
Ligand-Target Pair