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BDBM37988 1-((2-((4-(((1,1,1,3,3,3-hexafluoropropan-2- yl)oxy)carbonyl)piperazin-1-yl)methyl)-6- (trifluoromethyl)phenoxy)methyl) cyclopropane-1-carboxylic acid::US10093635, Example 30

SMILES: OC(=O)C1(COc2c(CN3CCN(CC3)C(=O)OC(C(F)(F)F)C(F)(F)F)cccc2C(F)(F)F)CC1

InChI Key: InChIKey=QQAJBYOIKVRWSM-UHFFFAOYSA-N

Data: 1 IC50

Find this compound or compounds like it in BindingDB or PDB:
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Similarity at least:  must be >=0.5
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Activity Spreadsheet -- Enzyme Inhibition Constant Data from BindingDB

Found 1 hit for monomerid = 37988   
Target/Host
(Institution)
LigandTarget/Host
Links
Ligand
Links
Trg + Lig
Links
Ki
nM
ΔG°
kcal/mole
IC50
nM
Kd
nM
EC50/IC50
nM
koff
s-1
kon
M-1s-1
pHTemp
°C
Monoglyceride lipase


(Homo sapiens (Human))
BDBM37988
PNG
(1-((2-((4-(((1,1,1,3,3,3-hexafluoropropan-2- yl)ox...)
Show SMILES OC(=O)C1(COc2c(CN3CCN(CC3)C(=O)OC(C(F)(F)F)C(F)(F)F)cccc2C(F)(F)F)CC1
Show InChI InChI=1S/C13H23N3O2S/c1-5-16(6-2)7-8-19-13-14-11(17)10(9(3)4)12(18)15-13/h9H,5-8H2,1-4H3,(H2,14,15,17,18)
PDB
MMDB

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Similars

US Patent
n/an/a 5.50E+3n/an/an/an/an/a25



ABIDE THERAPEUTICS, INC.

US Patent


Assay Description
Proteomes (human prefrontal cortex or cell membrane fractions) (50 μL, 1.0-2.0 mg/mL total protein concentration) were preincubated with varying...


US Patent US10093635 (2018)


BindingDB Entry DOI: 10.7270/Q2FF3VD0
More data for this
Ligand-Target Pair