BDBM380537 US9926318, C114 entB

SMILES OC(=O)CCN1C(=O)[C@@H]2Cc3c(CN2C1=O)n(Cc1ccc(F)cc1)c1ccccc31


Data  1 IC50

PDB links: 1 PDB ID matches this monomer.

Find this compound or compounds like it in BindingDB:
Similarity at least:  must be >=0.5
Exact match

Activity Spreadsheet -- Enzyme Inhibition Constant Data from BindingDB

Found 1 hit for monomerid = 380537   

TargetEctonucleotide pyrophosphatase/phosphodiesterase family member 2(Homo sapiens (Human))
PharmAkea Inc

US Patent
LigandPNGBDBM380537(US9926318, C114 entB)
Show SMILES OC(=O)CCN1C(=O)[C@@H]2Cc3c(CN2C1=O)n(Cc1ccc(F)cc1)c1ccccc31
Show InChI InChI=1S/C23H20FN3O4/c24-15-7-5-14(6-8-15)12-26-18-4-2-1-3-16(18)17-11-19-22(30)25(10-9-21(28)29)23(31)27(19)13-20(17)26/h1-8,19H,9-13H2,(H,28,29)/t19-/m0/s1
Affinity DataIC50: 500nMAssay Description:ATX activity is assayed in concentrated conditioned media from Hep3B human hepatocellular carcinoma cells by measuring the amount of choline released...More data for this Ligand-Target Pair
Ligand InfoPC cidPC sidPDB