BDBM402076 N-(2-((4,6-dimethylpyrimidin-2-yl)(ethyl)amino)ethyl)-N-ethyl-2-(2H-H-1,2,3-triazol-2-yl)benzamide::US10011595, C-1

SMILES CCN(CCN(CC)c1nc(C)cc(C)n1)C(=O)c1ccccc1-n1nccn1

InChI Key InChIKey=VACXGDAMAVWGEM-UHFFFAOYSA-N

Data  2 IC50

  Tab Delimited (TSV)   2D SDfile   Computed 3D by Vconf -m prep SDfile
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Activity Spreadsheet -- Enzyme Inhibition Constant Data from BindingDB

Found 2 hits for monomerid = 402076   

TargetOrexin/Hypocretin receptor type 1(Homo sapiens (Human))
Merck Sharp & Dohme

US Patent
LigandPNGBDBM402076(N-(2-((4,6-dimethylpyrimidin-2-yl)(ethyl)amino)eth...)
Affinity DataIC50:  3.17E+3nMAssay Description:In a typical experiment the OX1 and OX2 receptor antagonistic activity of the compounds of the present invention was determined in accordance with th...More data for this Ligand-Target Pair
Ligand InfoPC cidPC sid
In DepthDetails US Patent
TargetOrexin receptor type 2(Homo sapiens (Human))
Merck Sharp & Dohme

US Patent
LigandPNGBDBM402076(N-(2-((4,6-dimethylpyrimidin-2-yl)(ethyl)amino)eth...)
Affinity DataIC50:  36.6nMAssay Description:In a typical experiment the OX1 and OX2 receptor antagonistic activity of the compounds of the present invention was determined in accordance with th...More data for this Ligand-Target Pair
Ligand InfoPC cidPC sid
In DepthDetails US Patent