BDBM403656 (4aR,8S,11 S,12S,13R,25aR)-8-tert-butyl-N-[(1R,2R)-1-[(cyclopropylsulfonyl)carbamoyl]-2-(difluoromethyl)cyclopropyl]-12-ethyl-17-methoxy-6,9-dioxo-2,3,4,4a,6,7,8,9,12,13,21,22,23,24,25,25a-hexadecahydro-1H,11H-10,13-methanoquinoxalino[2,3-k][1,10,3,6]benzodioxadiazacyclononadecine-11-carboxamide::US10335409, Example 66

SMILES CC[C@@H]1[C@@H]2CN([C@@H]1C(=O)N[C@@]1(C[C@H]1C(F)F)C(=O)NS(=O)(=O)C1CC1)C(=O)[C@@H](NC(=O)O[C@@H]1CCC=C[C@H]1CCCCCc1nc3ccc(OC)cc3nc1O2)C(C)(C)C

InChI Key InChIKey=IVMFLSATEUJHTE-WVRZBAKZSA-N

Data  2 KI

  Tab Delimited (TSV)   2D SDfile   Computed 3D by Vconf -m prep SDfile
Find this compound or compounds like it in BindingDB:
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Exact match

Activity Spreadsheet -- Enzyme Inhibition Constant Data from BindingDB

Found 2 hits for monomerid = 403656   

TargetGenome polyprotein(Hepatitis C Virus (Virus))
Gilead Pharmasset

US Patent
LigandPNGBDBM403656((4aR,8S,11 S,12S,13R,25aR)-8-tert-butyl-N-[(1R,2R)...)
Affinity DataKi:  0.0400nMAssay Description:Purified NS3 protease domain (amino acids 1-181) of the genotype 1b and 3a virus were generated as above. The internally quenched fluorogenic depsipe...More data for this Ligand-Target Pair
Ligand InfoPC cidPC sid
In DepthDetails US Patent
TargetGenome polyprotein(Hepatitis C virus genotype 3a (isolate k3a) (HCV))
Gilead Pharmasset

US Patent
LigandPNGBDBM403656((4aR,8S,11 S,12S,13R,25aR)-8-tert-butyl-N-[(1R,2R)...)
Affinity DataKi:  0.0600nMAssay Description:Purified NS3 protease domain (amino acids 1-181) of the genotype 1b and 3a virus were generated as above. The internally quenched fluorogenic depsipe...More data for this Ligand-Target Pair
Ligand InfoPC cidPC sid
In DepthDetails US Patent