BDBM403660 (1aS,2aR,6S,9S,10S,11R,23aR,23bS)-6-tert-butyl-N-[(1R,2R)-1-[(cyclopropylsulfonyl)carbamoyl]-2-(difluoromethyl)cyclopropyl]-10-ethyl-15-methoxy-4,7-dioxo-1a,2,2a,4,5,6,7,10,11,19,20,21,22,23,23a,23b-hexadecahydro-1H,9H-8,11-methanocyclopropa[4′,5′]cyclopenta[1′,2′:18,19][1,10,3,6]dioxadiazacyclononadecino[11,12-b]quinoxaline-9-carboxamide::US10335409, Example 70
SMILES CC[C@@H]1[C@H](CN([C@@H]1C(=O)OC(C)(C)C)C(=O)[C@@H](NC(=O)O[C@@H]1C[C@@H]2C[C@@H]2[C@H]1CCCC=C)C(C)(C)C)Oc1nc2cc(OC)ccc2nc1Cl
InChI Key InChIKey=JDBOVBRLMSOBAE-QHEDQUORSA-N
Data 2 KI
Activity Spreadsheet -- Enzyme Inhibition Constant Data from BindingDB
Found 2 hits for monomerid = 403660
TargetGenome polyprotein(Hepatitis C virus genotype 3a (isolate k3a) (HCV))
Gilead Pharmasset
US Patent
Gilead Pharmasset
US Patent
Affinity DataKi: 0.0500nMAssay Description:Purified NS3 protease domain (amino acids 1-181) of the genotype 1b and 3a virus were generated as above. The internally quenched fluorogenic depsipe...More data for this Ligand-Target Pair
Affinity DataKi: 0.0500nMAssay Description:Purified NS3 protease domain (amino acids 1-181) of the genotype 1b and 3a virus were generated as above. The internally quenched fluorogenic depsipe...More data for this Ligand-Target Pair