BDBM404503 (R)-N-(1-cyanopyrrolidin-3-yl)-1-(cyclopropylmethyl)-6-(3, 5-dimethylisoxazol-4-yl)-1H-indazole-3-carboxamide::US10343992, Example 155::US10689345, Example 155::US11053198, Example 155::US11066365, Example 155::US11390584, Example 155
SMILES Cc1noc(C)c1-c1ccc2c(nn(CC3CC3)c2c1)C(=O)N[C@@H]1CCN(C1)C#N
InChI Key InChIKey=CGYUQCMKKVYZJQ-QGZVFWFLSA-N
Data 5 IC50
Activity Spreadsheet -- Enzyme Inhibition Constant Data from BindingDB
Found 5 hits for monomerid = 404503
Affinity DataIC50: <100nMAssay Description:Dilution plates were prepared at 21 times the final concentration (2100 μM for a final concentration of 100 μM) in 50% DMSO in a 96-well po...More data for this Ligand-Target Pair
Affinity DataIC50: <100nMAssay Description:USP30 Biochemical Fluorescence Intensity Kinetic Assay.Reactions were performed in duplicate in black 384 well plates (small volume, Greiner 784076) ...More data for this Ligand-Target Pair
Affinity DataIC50: <100nMAssay Description:Dilution plates were prepared at 21 times the final concentration (2100 μM for a final concentration of 100 μM) in 50% DMSO in a 96-well po...More data for this Ligand-Target Pair
Affinity DataIC50: <100nMAssay Description:Dilution plates were prepared at 21 times the final concentration (2100 μM for a final concentration of 100 μM) in 50% DMSO in a 96-well po...More data for this Ligand-Target Pair
Affinity DataIC50: <100nMAssay Description:USP30 biochemical fluorescence intensity IC50 assay Dilution plates were prepared at 21 times the final concentration (2100 μM for a final conce...More data for this Ligand-Target Pair