BDBM408141 2-(4-(1-(Benzo[d][1,3]dioxol-5-yl)ethyl)piperazin-1-yl)-N-propylpyrimidin-4-amine::US10336775, Example 45::US11046712, No 45

SMILES CCCNc1ccnc(n1)N1CCN(CC1)C(C)c1ccc2OCOc2c1

InChI Key InChIKey=XPKYFYGYZVGJGB-UHFFFAOYSA-N

Data  2 IC50

  Tab Delimited (TSV)   2D SDfile   Computed 3D by Vconf -m prep SDfile
Find this compound or compounds like it in BindingDB:
   Substructure
Similarity at least:  must be >=0.5
Exact match

Activity Spreadsheet -- Enzyme Inhibition Constant Data from BindingDB

Found 2 hits for monomerid = 408141   

TargetProtein O-GlcNAcase(Homo sapiens (Human))
Asceneuron

US Patent
LigandPNGBDBM408141(2-(4-(1-(Benzo[d][1,3]dioxol-5-yl)ethyl)piperazin-...)
Affinity DataIC50:  600nMAssay Description:5 μI of the appropriate concentration of a solution of inhibitor in McIlvaine's Buffer (pH 6.5) in 2% DMSO (for a dose response curve calcul...More data for this Ligand-Target Pair
Ligand InfoPC cidPC sid
In DepthDetails US Patent
TargetProtein O-GlcNAcase(Homo sapiens (Human))
Asceneuron

US Patent
LigandPNGBDBM408141(2-(4-(1-(Benzo[d][1,3]dioxol-5-yl)ethyl)piperazin-...)
Affinity DataIC50:  600nMAssay Description:5 μl of the appropriate concentration of a solution of inhibitor in McIlvaine's Buffer (pH 6.5) in 2% DMSO (for a dose response curve calcul...More data for this Ligand-Target Pair
Ligand InfoPC cidPC sid
In DepthDetails US Patent