BDBM408206 N-(5-(4-(1-(benzo[d][1,3]dioxol-5-yl)ethyl)piperazin-1-yl)-1,3,4-thiadiazol-2-yl)-4-chlorobenzamide::US10336775, Example 110::US11046712, No 110

SMILES CC(N1CCN(CC1)c1nnc(NC(=O)c2ccc(Cl)cc2)s1)c1ccc2OCOc2c1

InChI Key InChIKey=JDXUHBQIYVVYPL-UHFFFAOYSA-N

Data  2 IC50

  Tab Delimited (TSV)   2D SDfile   Computed 3D by Vconf -m prep SDfile
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Similarity at least:  must be >=0.5
Exact match

Activity Spreadsheet -- Enzyme Inhibition Constant Data from BindingDB

Found 2 hits for monomerid = 408206   

TargetProtein O-GlcNAcase(Homo sapiens (Human))
Asceneuron

US Patent
LigandPNGBDBM408206(N-(5-(4-(1-(benzo[d][1,3]dioxol-5-yl)ethyl)piperaz...)
Affinity DataIC50:  125nMAssay Description:5 μI of the appropriate concentration of a solution of inhibitor in McIlvaine's Buffer (pH 6.5) in 2% DMSO (for a dose response curve calcul...More data for this Ligand-Target Pair
Ligand InfoPC cidPC sid
In DepthDetails US Patent
TargetProtein O-GlcNAcase(Homo sapiens (Human))
Asceneuron

US Patent
LigandPNGBDBM408206(N-(5-(4-(1-(benzo[d][1,3]dioxol-5-yl)ethyl)piperaz...)
Affinity DataIC50:  125nMAssay Description:5 μl of the appropriate concentration of a solution of inhibitor in McIlvaine's Buffer (pH 6.5) in 2% DMSO (for a dose response curve calcul...More data for this Ligand-Target Pair
Ligand InfoPC cidPC sid
In DepthDetails US Patent