BDBM408216 N-(2-(4-(1-(quinolin-7-yl)ethyl)piperazin-1-yl)pyrimidin-5-yl)acetamide::US10336775, Example 120::US11046712, No 120

SMILES CC(N1CCN(CC1)c1ncc(NC(C)=O)cn1)c1ccc2cccnc2c1

InChI Key InChIKey=XRZCXUMUKPDZBA-UHFFFAOYSA-N

Data  2 IC50

  Tab Delimited (TSV)   2D SDfile   Computed 3D by Vconf -m prep SDfile
Find this compound or compounds like it in BindingDB:
   Substructure
Similarity at least:  must be >=0.5
Exact match

Activity Spreadsheet -- Enzyme Inhibition Constant Data from BindingDB

Found 2 hits for monomerid = 408216   

TargetProtein O-GlcNAcase(Homo sapiens (Human))
Asceneuron

US Patent
LigandPNGBDBM408216(N-(2-(4-(1-(quinolin-7-yl)ethyl)piperazin-1-yl)pyr...)
Affinity DataIC50:  600nMAssay Description:5 μI of the appropriate concentration of a solution of inhibitor in McIlvaine's Buffer (pH 6.5) in 2% DMSO (for a dose response curve calcul...More data for this Ligand-Target Pair
Ligand InfoPC cidPC sid
In DepthDetails US Patent
TargetProtein O-GlcNAcase(Homo sapiens (Human))
Asceneuron

US Patent
LigandPNGBDBM408216(N-(2-(4-(1-(quinolin-7-yl)ethyl)piperazin-1-yl)pyr...)
Affinity DataIC50:  125nMAssay Description:5 μl of the appropriate concentration of a solution of inhibitor in McIlvaine's Buffer (pH 6.5) in 2% DMSO (for a dose response curve calcul...More data for this Ligand-Target Pair
Ligand InfoPC cidPC sid
In DepthDetails US Patent