BDBM417704 2-[6-(5-chloro-2- {[trans-4- methoxycyclohexyl] amino}pyrimidin-4-yl)- 1-oxo-2,3-dihydro-1H- isoindol-2-yl]-N-[(1S)- 2-hydroxy-1-(3- methoxyphenyl)ethyl] acetamide::US10457669, Example 324::US11001575, Example 324

SMILES CO[C@H]1CC[C@@H](CC1)Nc1ncc(Cl)c(n1)-c1ccc2CN(CC(=O)N[C@H](CO)c3cccc(OC)c3)C(=O)c2c1

InChI Key InChIKey=NFFRFWNSZBBFDE-XLGIIRLISA-N

Data  2 IC50

  Tab Delimited (TSV)   2D SDfile   Computed 3D by Vconf -m prep SDfile
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Similarity at least:  must be >=0.5
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Activity Spreadsheet -- Enzyme Inhibition Constant Data from BindingDB

Found 2 hits for monomerid = 417704   

TargetMitogen-activated protein kinase 1(Homo sapiens (Human))
Otsuka Pharmaceutical

US Patent
LigandPNGBDBM417704(2-[6-(5-chloro-2- {[trans-4- methoxycyclohexyl] am...)
Affinity DataIC50:  1.90nMAssay Description:Activity of ERK2 enzyme (Life Technologies) was determined using a time-resolved fluorescence format measuring the phosphorylation of a truncated ver...More data for this Ligand-Target Pair
Ligand InfoPC cidPC sid
In DepthDetails US Patent
TargetMitogen-activated protein kinase 1(Homo sapiens (Human))
Otsuka Pharmaceutical

US Patent
LigandPNGBDBM417704(2-[6-(5-chloro-2- {[trans-4- methoxycyclohexyl] am...)
Affinity DataIC50:  1.90nMAssay Description:Activity of ERK2 enzyme (Life Technologies) was determined using a time-resolved fluorescence format measuring the phosphorylation of a truncated ver...More data for this Ligand-Target Pair
Ligand InfoPC cidPC sid
In DepthDetails US Patent