BDBM417819 US10457669, Example 463::US11001575, Example 463

SMILES COc1ccc2CCC(CO)(NC(=O)CN3Cc4ccc(cc4C3=O)-c3nc(NC4CCOCC4)ncc3Cl)c2c1

InChI Key InChIKey=CANKFTMCDFSNOK-UHFFFAOYSA-N

Data  2 IC50

  Tab Delimited (TSV)   2D SDfile   Computed 3D by Vconf -m prep SDfile
Find this compound or compounds like it in BindingDB:
   Substructure
Similarity at least:  must be >=0.5
Exact match

Activity Spreadsheet -- Enzyme Inhibition Constant Data from BindingDB

Found 2 hits for monomerid = 417819   

TargetMitogen-activated protein kinase 1(Homo sapiens (Human))
Otsuka Pharmaceutical

US Patent
LigandPNGBDBM417819(US10457669, Example 463 | US11001575, Example 463)
Affinity DataIC50:  2nMAssay Description:Activity of ERK2 enzyme (Life Technologies) was determined using a time-resolved fluorescence format measuring the phosphorylation of a truncated ver...More data for this Ligand-Target Pair
Ligand InfoPC cidPC sid
In DepthDetails US Patent
TargetMitogen-activated protein kinase 1(Homo sapiens (Human))
Otsuka Pharmaceutical

US Patent
LigandPNGBDBM417819(US10457669, Example 463 | US11001575, Example 463)
Affinity DataIC50:  2nMAssay Description:Activity of ERK2 enzyme (Life Technologies) was determined using a time-resolved fluorescence format measuring the phosphorylation of a truncated ver...More data for this Ligand-Target Pair
Ligand InfoPC cidPC sid
In DepthDetails US Patent