BDBM418101 (2R)-2-(6-{5-chloro-2-[(2- methylpyrimidin-4-yl)amino]pyrimidin- 4-yl}-1-oxo-2,3-dihydro-1H-isoindol-2- yl)-N-[(1S)-1-(3-fluoro-5- methylphenyl)-2- hydroxyethyl]propanamide::US10457669, Example 823::US11001575, Example 823
SMILES C[C@@H](N1Cc2ccc(cc2C1=O)-c1nc(Nc2ccnc(C)n2)ncc1Cl)C(=O)N[C@H](CO)c1cc(C)cc(F)c1
InChI Key InChIKey=AMGJEPSJFWYNAY-VOIUYBSRSA-N
Data 2 IC50
Activity Spreadsheet -- Enzyme Inhibition Constant Data from BindingDB
Found 2 hits for monomerid = 418101
Affinity DataIC50: 1.90nMAssay Description:Activity of ERK2 enzyme (Life Technologies) was determined using a time-resolved fluorescence format measuring the phosphorylation of a truncated ver...More data for this Ligand-Target Pair
Affinity DataIC50: 1.90nMAssay Description:Activity of ERK2 enzyme (Life Technologies) was determined using a time-resolved fluorescence format measuring the phosphorylation of a truncated ver...More data for this Ligand-Target Pair