BDBM419158 US10457637, Compound 22::ethanesulfinyl-N-(4- ethylphenyl)-N-isobutyl- 4-(tetrahydropyran-4- ylmethoxy)benzene- sulfonamide

SMILES CCc1ccc(cc1)N(CC(C)C)S(=O)(=O)c1ccc(OCC2CCOCC2)c(c1)S(=O)CC

InChI Key InChIKey=RKEKMGUGGBHNDU-UHFFFAOYSA-N

Data  2 IC50

  Tab Delimited (TSV)   2D SDfile   Computed 3D by Vconf -m prep SDfile
Find this compound or compounds like it in BindingDB:
   Substructure
Similarity at least:  must be >=0.5
Exact match

Activity Spreadsheet -- Enzyme Inhibition Constant Data from BindingDB

Found 2 hits for monomerid = 419158   

TargetInterleukin-17A(Homo sapiens (Human))
Galderma Research & Development

US Patent
LigandPNGBDBM419158(US10457637, Compound 22 | ethanesulfinyl-N-(4- eth...)
Affinity DataIC50:  550nMAssay Description:This model allows measurement of the effect of inhibitors on IL-17A secretion by CD4+ cells. The cells are frozen CD4+ cells (STEMCELL, #70026), isol...More data for this Ligand-Target Pair
Ligand InfoPC cidPC sid
In DepthDetails US Patent
TargetNuclear receptor ROR-gamma(Homo sapiens (Human))
Galderma Research & Development

US Patent
LigandPNGBDBM419158(US10457637, Compound 22 | ethanesulfinyl-N-(4- eth...)
Affinity DataIC50:  550nMAssay Description:The RORγ transactivation model was developed from the line HG5LN, which is a HeLa line that stably expresses a luciferase reporter gene controll...More data for this Ligand-Target Pair
Ligand InfoPC cidPC sid
In DepthDetails US Patent