BDBM420279 SX-626::USRE47740, Compound 9::USRE48547, Compound 9

SMILES CN(Cc1ccccc1O)c1ccc(cn1)C(=O)Nc1ccc(F)cc1

InChI Key InChIKey=WTPHZYHGFKLDGS-UHFFFAOYSA-N

Data  2 IC50

  Tab Delimited (TSV)   2D SDfile   Computed 3D by Vconf -m prep SDfile
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Activity Spreadsheet -- Enzyme Inhibition Constant Data from BindingDB

Found 2 hits for monomerid = 420279   

TargetC-X-C chemokine receptor type 2(Homo sapiens (Human))
Syntrix Biosystems

US Patent
LigandPNGBDBM420279(SX-626 | USRE47740, Compound 9 | USRE48547, Compou...)
Affinity DataIC50:  586nMAssay Description:An in vitro assay showed inhibition of CXCR2-mediated intracellular calcium release by treatment with compound 9 (IC50=586±91 nM). Briefly, human neu...More data for this Ligand-Target Pair
Ligand Info
In DepthDetails US Patent
TargetC-X-C chemokine receptor type 2(Homo sapiens (Human))
Syntrix Biosystems

US Patent
LigandPNGBDBM420279(SX-626 | USRE47740, Compound 9 | USRE48547, Compou...)
Affinity DataIC50:  586nMAssay Description:Briefly, human neutrophils were suspended in HBSS− (without Ca2+ and Mg2+) containing 10 mM HEPES and FLIPR Calcium 3 dye (3.1×107 cells in tot...More data for this Ligand-Target Pair
Ligand Info
In DepthDetails US Patent