BDBM423621 US10508120, Compound I-76::US10577373, Compound I-76::US11046698, Compound I-76
SMILES NC(=O)c1cnn2c(N)cc(Nc3cccn([C@@H]4CC[C@@H](CC4)N4CCOCC4)c3=O)nc12
InChI Key InChIKey=AYFJJSXLHKUJHG-GASCZTMLSA-N
Data 3 Kd
Activity Spreadsheet -- Enzyme Inhibition Constant Data from BindingDB
Found 3 hits for monomerid = 423621
TargetNon-receptor tyrosine-protein kinase TYK2 [556-888](Homo sapiens (Human))
Nimbus Lakshimi
US Patent
Nimbus Lakshimi
US Patent
Affinity DataKd: 5.5nMAssay Description:Binding constants for compounds of the present invention against the JH2 domain were determined by the following protocol for a KINOMEscan® assay (Di...More data for this Ligand-Target Pair
TargetNon-receptor tyrosine-protein kinase TYK2 [556-888](Homo sapiens (Human))
Nimbus Lakshimi
US Patent
Nimbus Lakshimi
US Patent
Affinity DataKd: 5.5nMAssay Description:Binding constants for compounds of the present invention against the JH2 domain were determined by the following protocol for a KINOMEscan® assay (Di...More data for this Ligand-Target Pair
TargetNon-receptor tyrosine-protein kinase TYK2 [556-888](Homo sapiens (Human))
Nimbus Lakshimi
US Patent
Nimbus Lakshimi
US Patent
Affinity DataKd: 5.5nMAssay Description:Binding constants for compounds of the present invention against the JH2 domain were determined by the following protocol for a KINOMEscan® assay (Di...More data for this Ligand-Target Pair