BDBM423713 US10508120, Compound I-168::US10577373, Compound I-168::US11046698, Compound I-168
SMILES CNc1cc(Nc2cccnc2OC2CCC2)nc2c(cnn12)C(=O)NC1CCC1
InChI Key InChIKey=RONBRMLSSYXMHY-UHFFFAOYSA-N
Data 3 Kd
Activity Spreadsheet -- Enzyme Inhibition Constant Data from BindingDB
Found 3 hits for monomerid = 423713
TargetNon-receptor tyrosine-protein kinase TYK2 [556-888](Homo sapiens (Human))
Nimbus Lakshimi
US Patent
Nimbus Lakshimi
US Patent
Affinity DataKd: 0.600nMAssay Description:Binding constants for compounds of the present invention against the JH2 domain were determined by the following protocol for a KINOMEscan® assay (Di...More data for this Ligand-Target Pair
TargetNon-receptor tyrosine-protein kinase TYK2 [556-888](Homo sapiens (Human))
Nimbus Lakshimi
US Patent
Nimbus Lakshimi
US Patent
Affinity DataKd: 0.600nMAssay Description:Binding constants for compounds of the present invention against the JH2 domain were determined by the following protocol for a KINOMEscan® assay (Di...More data for this Ligand-Target Pair
TargetNon-receptor tyrosine-protein kinase TYK2 [556-888](Homo sapiens (Human))
Nimbus Lakshimi
US Patent
Nimbus Lakshimi
US Patent
Affinity DataKd: 0.600nMAssay Description:Binding constants for compounds of the present invention against the JH2 domain were determined by the following protocol for a KINOMEscan® assay (Di...More data for this Ligand-Target Pair