BDBM424741 US10508120, Compound I-1245::US10508120, Compound I-1361::US10577373, Compound I-1245::US11046698, Compound I-1361
SMILES CNc1cc(Nc2cccn([C@H]3CCC[C@H](C3)C#N)c2=O)nc2c(cnn12)C(=O)NC1CC1
InChI Key InChIKey=DTXZHRGMBVNAMD-ZBFHGGJFSA-N
Data 6 Kd
Activity Spreadsheet -- Enzyme Inhibition Constant Data from BindingDB
Found 6 hits for monomerid = 424741
TargetNon-receptor tyrosine-protein kinase TYK2 [556-888](Homo sapiens (Human))
Nimbus Lakshimi
US Patent
Nimbus Lakshimi
US Patent
Affinity DataKd: 0.600nMAssay Description:Binding constants for compounds of the present invention against the JH2 domain were determined by the following protocol for a KINOMEscan® assay (Di...More data for this Ligand-Target Pair
TargetNon-receptor tyrosine-protein kinase TYK2 [556-888](Homo sapiens (Human))
Nimbus Lakshimi
US Patent
Nimbus Lakshimi
US Patent
Affinity DataKd: 0.600nMAssay Description:Binding constants for compounds of the present invention against the JH2 domain were determined by the following protocol for a KINOMEscan® assay (Di...More data for this Ligand-Target Pair
TargetNon-receptor tyrosine-protein kinase TYK2 [556-888](Homo sapiens (Human))
Nimbus Lakshimi
US Patent
Nimbus Lakshimi
US Patent
Affinity DataKd: 0.600nMAssay Description:Binding constants for compounds of the present invention against the JH2 domain were determined by the following protocol for a KINOMEscan® assay (Di...More data for this Ligand-Target Pair
TargetNon-receptor tyrosine-protein kinase TYK2 [556-888](Homo sapiens (Human))
Nimbus Lakshimi
US Patent
Nimbus Lakshimi
US Patent
Affinity DataKd: 0.600nMAssay Description:Binding constants for compounds of the present invention against the JH2 domain were determined by the following protocol for a KINOMEscan® assay (Di...More data for this Ligand-Target Pair
TargetNon-receptor tyrosine-protein kinase TYK2 [556-888](Homo sapiens (Human))
Nimbus Lakshimi
US Patent
Nimbus Lakshimi
US Patent
Affinity DataKd: 0.600nMAssay Description:Binding constants for compounds of the present invention against the JH2 domain were determined by the following protocol for a KINOMEscan® assay (Di...More data for this Ligand-Target Pair
TargetNon-receptor tyrosine-protein kinase TYK2 [556-888](Homo sapiens (Human))
Nimbus Lakshimi
US Patent
Nimbus Lakshimi
US Patent
Affinity DataKd: 0.600nMAssay Description:Binding constants for compounds of the present invention against the JH2 domain were determined by the following protocol for a KINOMEscan® assay (Di...More data for this Ligand-Target Pair