BDBM424919 US10517849, Compound 23::US11013718, Compound 23::US11547695, Compound 23
SMILES CC\C(=C/c1ccccc1)[C@@H]1C[C@H]1NC1CC2(C1)CCN(CCS(N)(=O)=O)CC2
InChI Key InChIKey=OHMWNRGWKVNFAG-ISHKIFBASA-N
Data 3 IC50
Activity Spreadsheet -- Enzyme Inhibition Constant Data from BindingDB
Found 3 hits for monomerid = 424919
TargetLysine-specific histone demethylase 1A(Homo sapiens (Human))
Constellation Pharmaceuticals
US Patent
Constellation Pharmaceuticals
US Patent
Affinity DataIC50: <100nMAssay Description:LSD1 demethylase reactions were carried out in 50 mM HEPES pH 7.4, 100 mM NaCl, 1 mM DTT, 0.01% Tween-20, and 0.1 mg/mL BSA. All enzymatic reactions ...More data for this Ligand-Target Pair
TargetLysine-specific histone demethylase 1A(Homo sapiens (Human))
Constellation Pharmaceuticals
US Patent
Constellation Pharmaceuticals
US Patent
Affinity DataIC50: <100nMAssay Description:LSD1 demethylase reactions were carried out in 50 mM HEPES pH 7.4, 100 mM NaCl, 1 mM DTT, 0.01% Tween-20, and 0.1 mg/mL BSA. All enzymatic reactions ...More data for this Ligand-Target Pair
TargetLysine-specific histone demethylase 1A(Homo sapiens (Human))
Constellation Pharmaceuticals
US Patent
Constellation Pharmaceuticals
US Patent
Affinity DataIC50: <100nMAssay Description:LSD1 demethylase reactions were carried out in 50 mM HEPES pH 7.4, 100 mM NaCl, 1 mM DTT, 0.01% Tween-20, and 0.1 mg/mL BSA. All enzymatic reactions ...More data for this Ligand-Target Pair