BDBM4273 N-[4-(2,2-dicyanoeth-1-en-1-yl)phenyl]acetamide::Tyrphostin deriv. 3

SMILES [#6]-[#6](=O)-[#7]-c1ccc(\[#6]=[#6](/C#N)C#N)cc1

InChI Key InChIKey=HDJOIOGUBRECCC-UHFFFAOYSA-N

Data  1 IC50

  Tab Delimited (TSV)   2D SDfile   Computed 3D by Vconf -m prep SDfile
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Similarity at least:  must be >=0.5
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Activity Spreadsheet -- Enzyme Inhibition Constant Data from BindingDB

Found 1 hit for monomerid = 4273   

TargetEpidermal growth factor receptor(Homo sapiens (Human))
Hebrew University Of Jerusalem

LigandPNGBDBM4273(N-[4-(2,2-dicyanoeth-1-en-1-yl)phenyl]acetamide | ...)
Affinity DataIC50: >3.25E+5nMpH: 7.6 T: 2°CAssay Description:The activity of EGFR, preactivated with EGF, is measured by its ability to transfer terminal phosphate from [gamma-32P]ATP to poly(GAT) substrate.More data for this Ligand-Target Pair
In DepthDetails ArticlePubMed