BDBM4276 2-[(3-fluoro-4-methoxyphenyl)methylidene]propanedinitrile::Tyrphostin deriv. 6

SMILES [#6]-[#8]-c1ccc(\[#6]=[#6](/C#N)C#N)cc1F

InChI Key InChIKey=KCRDGGROWVQVJO-UHFFFAOYSA-N

Data  1 IC50

  Tab Delimited (TSV)   2D SDfile   Computed 3D by Vconf -m prep SDfile
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Activity Spreadsheet -- Enzyme Inhibition Constant Data from BindingDB

Found 1 hit for monomerid = 4276   

TargetEpidermal growth factor receptor(Homo sapiens (Human))
Hebrew University Of Jerusalem

LigandPNGBDBM4276(2-[(3-fluoro-4-methoxyphenyl)methylidene]propanedi...)
Affinity DataIC50:  8.00E+5nMpH: 7.6 T: 2°CAssay Description:The activity of EGFR, preactivated with EGF, is measured by its ability to transfer terminal phosphate from [gamma-32P]ATP to poly(GAT) substrate.More data for this Ligand-Target Pair
In DepthDetails ArticlePubMed