BDBM4286 (4,5-Dihydroxyindanylidene)malononitrile::2-(4,5-dihydroxy-2,3-dihydro-1H-inden-1-ylidene)propanedinitrile::Tyrphostin deriv. 17

SMILES [#8]-c1ccc2\[#6](-[#6]-[#6]-c2c1-[#8])=[#6](/C#N)C#N

InChI Key InChIKey=QNMCUDUCYPYEQM-UHFFFAOYSA-N

Data  2 IC50

  Tab Delimited (TSV)   2D SDfile   Computed 3D by Vconf -m prep SDfile
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Similarity at least:  must be >=0.5
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Activity Spreadsheet -- Enzyme Inhibition Constant Data from BindingDB

Found 2 hits for monomerid = 4286   

TargetEpidermal growth factor receptor(Homo sapiens (Human))
TBA

Curated by ChEMBL
LigandPNGBDBM4286((4,5-Dihydroxyindanylidene)malononitrile | 2-(4,5-...)
Affinity DataIC50:  7.00E+3nMAssay Description:Inhibition of EGFR in human A431 cellsMore data for this Ligand-Target Pair
In DepthDetails ArticlePubMed
TargetEpidermal growth factor receptor(Homo sapiens (Human))
TBA

Curated by ChEMBL
LigandPNGBDBM4286((4,5-Dihydroxyindanylidene)malononitrile | 2-(4,5-...)
Affinity DataIC50:  7.00E+3nMpH: 7.6 T: 2°CAssay Description:The activity of EGFR, preactivated with EGF, is measured by its ability to transfer terminal phosphate from [gamma-32P]ATP to poly(GAT) substrate.More data for this Ligand-Target Pair
In DepthDetails ArticlePubMed