BDBM429100 MPI8::jm5b01461, Compound 45

SMILES CC(OC(C)(C)C)[C@H](NC(=O)OCc1ccccc1)C(=O)N[C@@H](CC1CCCCC1)C(=O)N[C@@H](C[C@@H]1CCNC1=O)C=O

InChI Key InChIKey=YFUZVOLEKQFVCQ-OKCRAPNYSA-N

Data  4 KI  6 IC50

  Tab Delimited (TSV)   2D SDfile   Computed 3D by Vconf -m prep SDfile
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Activity Spreadsheet -- Enzyme Inhibition Constant Data from BindingDB

Found 9 hits for monomerid = 429100   

TargetReplicase polyprotein 1ab(Human SARS coronavirus (SARS-CoV) (Severe acute re...)
University Of Bonn

LigandPNGBDBM429100(MPI8 | jm5b01461, Compound 45)
Affinity DataKi:  53nMAssay Description:This is a review article.More data for this Ligand-Target Pair
Ligand InfoPC cidPC sid
In DepthDetails ArticlePubMed
TargetReplicase polyprotein 1ab(HCoV-229E)
University Of Bonn

LigandPNGBDBM429100(MPI8 | jm5b01461, Compound 45)
Affinity DataKi:  68nMAssay Description:This is a review article.More data for this Ligand-Target Pair
Ligand InfoPC cidPC sid
In DepthDetails ArticlePubMed
TargetReplicase polyprotein 1ab(2019-nCoV)
Texas A&M University

LigandPNGBDBM429100(MPI8 | jm5b01461, Compound 45)
Affinity DataKi:  103nM IC50:  105nMAssay Description:The assays were carried out with 20 nM enzyme (except for MPI3, for which 10 nM enzyme was used) and 10 μM substrate at 37oC with continuous sha...More data for this Ligand-Target Pair
Ligand InfoPC cidPC sid
In DepthDetails ArticlePubMed
TargetReplicase polyprotein 1ab(HCoV-229E)
University Of Bonn

LigandPNGBDBM429100(MPI8 | jm5b01461, Compound 45)
Affinity DataKi:  140nMAssay Description:This is a review article.More data for this Ligand-Target Pair
Ligand InfoPC cidPC sid
In DepthDetails ArticlePubMed
TargetCathepsin K(Homo sapiens (Human))
The University Of Arizona

LigandPNGBDBM429100(MPI8 | jm5b01461, Compound 45)
Affinity DataIC50:  180nMAssay Description:FRET-based enzymatic assay.More data for this Ligand-Target Pair
Ligand InfoPC cidPC sid
In DepthDetails ArticlePubMed
TargetReplicase polyprotein 1ab(2019-nCoV)
Texas A&M University

LigandPNGBDBM429100(MPI8 | jm5b01461, Compound 45)
Affinity DataIC50:  105nMAssay Description:FRET-based enzymatic assay.More data for this Ligand-Target Pair
Ligand InfoPC cidPC sid
In DepthDetails ArticlePubMed
TargetProcathepsin L(Homo sapiens (Human))
The University Of Arizona

LigandPNGBDBM429100(MPI8 | jm5b01461, Compound 45)
Affinity DataIC50:  1.20nMAssay Description:FRET-based enzymatic assay.More data for this Ligand-Target Pair
Ligand InfoPC cidPC sid
In DepthDetails ArticlePubMed
TargetCathepsin B(Homo sapiens (Human))
The University Of Arizona

LigandPNGBDBM429100(MPI8 | jm5b01461, Compound 45)
Affinity DataIC50:  230nMAssay Description:FRET-based enzymatic assay.More data for this Ligand-Target Pair
Ligand InfoPC cidPC sid
In DepthDetails ArticlePubMed
TargetReplicase polyprotein 1ab(Human SARS coronavirus (SARS-CoV) (Severe acute re...)
University Of Bonn

LigandPNGBDBM429100(MPI8 | jm5b01461, Compound 45)
Affinity DataIC50:  600nMAssay Description:This is a review article.More data for this Ligand-Target Pair
Ligand InfoPC cidPC sid
In DepthDetails ArticlePubMed